Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: SCRB1 (Q8WTV0)
Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)
Gene: SCARB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33144569
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001618 - virus receptor activity
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0033344 - cholesterol efflux
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 552
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024