HitPredict

Interactor 1: RGS12 (O14924)
Regulator of G-protein signaling 12 (RGS12)
Gene: RGS12

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~RBD
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1447 Hs			1 248
+	Hs
		168039 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		168041 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		168033 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		168034 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		168038 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		168044 RGS12_HUMAN (1-1447): 0: 1860: 100.00		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20
+	Hs
		890644 RGS3_HUMAN (23-236): 3.58e-25: 116: 14.95		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		690833 RGS3_HUMAN (23-236): 3.58e-25: 116: 14.95		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		729684 RGS3_HUMAN (23-236): 3.58e-25: 116: 14.95		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62