HitPredict

Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 36380368
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 649
+	Hs
		1085020 ARC1A_HUMAN (1-371): 6.17e-84: 261: 67.83		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		1270217 ARC1A_HUMAN (1-371): 6.17e-84: 261: 67.83		DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98
+	Hs
		1221289 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		RB12B_HUMAN (173-626): 1.39e-17: 89.1: 13.95
+	Hs
		1264784 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55
+	Sc
		551362 ARPC1_YEAST (96-366): 5.97e-09: 59.3: 9.82		ABP1_YEAST (4-508): 1.78e-30: 128: 13.51