HitPredict

Interactor 1: MUSK (O15146)
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
Gene: MUSK

Interactor 2: ARFG2 (Q8N6H7)
ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)
Gene: ARFGAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 869 Hs			1 521
+	Hs
		169208 MUSK_HUMAN (1-869): 0: 794: 100.00		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		434240 RET_HUMAN (493-869): 1.79e-118: 388: 33.85		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		434292 RET_HUMAN (493-869): 1.79e-118: 388: 33.85		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		508103 FGFR1_HUMAN (1-330): 4.65e-67: 241: 17.79		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		435771 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		508212 FGFR1_HUMAN (1-330): 4.65e-67: 241: 17.79		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		608147 FGFR4_HUMAN (10-301): 5.06e-66: 238: 18.26		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		434250 RET_HUMAN (493-869): 1.79e-118: 388: 33.85		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		1081534 NTRK3_HUMAN (28-203): 2.23e-19: 95.5: 25.26		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		1081615 NTRK3_HUMAN (28-203): 2.23e-19: 95.5: 25.26		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		729365 VGFR3_HUMAN (14-360): 3.3e-18: 92.5: 15.51		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		508092 FGFR1_HUMAN (1-330): 4.65e-67: 241: 17.79		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Hs
		601555 FGFR2_HUMAN (21-330): 7.1e-72: 255: 20.05		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		608038 FGFR4_HUMAN (10-301): 5.06e-66: 238: 18.26		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Hs
		608046 FGFR4_HUMAN (10-301): 5.06e-66: 238: 18.26		ARFG1_HUMAN (6-387): 1.44e-62: 211: 21.66
+	Hs
		508123 FGFR1_HUMAN (1-330): 4.65e-67: 241: 17.79		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		608061 FGFR4_HUMAN (10-301): 5.06e-66: 238: 18.26		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		968427 ROR2_HUMAN (30-121): 4.69e-20: 97.8: 27.66		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Hs
		968441 ROR2_HUMAN (30-121): 4.69e-20: 97.8: 27.66		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		385239 NTRK1_HUMAN (27-230): 3.5e-12: 72.4: 19.40		ARAP3_HUMAN (12-247): 1.56e-51: 191: 20.90