HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	24755078, 17110929
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_3, ubiquitin~zf-RanBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 685
+	Hs
		475639 MDM2_HUMAN (2-488): 0: 554: 31.56		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		923960 MDM2_HUMAN (2-488): 0: 554: 31.56		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		474998 MDM2_HUMAN (2-488): 0: 554: 31.56		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Rn
		88798 D3ZVH5_RAT (2-488): 0: 518: 28.43		UBC_RAT (1-108): 1.27e-29: 127: 90.74