Protein: CASQ2
Calsequestrin-2 (Calsequestrin, cardiac muscle isoform)

Gene: CASQ2
Organism: Homo sapiens
Interactions: 72
UniProt ID: O14958

Gene Ontology (top 5):
GO:0002027 - regulation of heart rate
GO:0005509 - calcium ion binding
GO:0005513 - detection of calcium ion
GO:0005737 - cytoplasm
GO:0006874 - intracellular calcium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

169226

OBSL1
Obscurin-like protein 1

3

6

High-throughput

0.667

High

169240

ACTA
Actin, aortic smooth muscle

3

4

High-throughput

0.667

High

169241

RS15
Small ribosomal subunit protein uS19

3

1

High-throughput

0.667

High

169250

CUL7
Cullin-7

3

5

High-throughput

0.667

High

169256

SULF2
Extracellular sulfatase Sulf-2

3

4

High-throughput

0.667

High

169258

FBXW8
F-box/WD repeat-containing protein 8

3

10

High-throughput

0.667

High

169259

NIN
Ninein

3

2

High-throughput

0.667

High

169268

NEB2
Neurabin-2

3

8

High-throughput

0.667

High

169271

CCDC8
Coiled-coil domain-containing protein 8

3

4

High-throughput

0.667

High

169272

E41LB
Band 4.1-like protein 4B

3

6

High-throughput

0.667

High

169277

KLH11
Kelch-like protein 11

3

2

High-throughput

0.667

High

169282

NEB1
Neurabin-1

3

6

High-throughput

0.667

High

169246

TRDN
Triadin

3

6

Small-scale

0.655

High

169222

CASQ2
Calsequestrin-2

1

13

Small-scale

0.647

High

169236

MARK3
MAP/microtubule affinity-regulating kinase 3

3

0

High-throughput

0.638

High

169280

DAXX
Death domain-associated protein 6

3

0

High-throughput

0.638

High

169227

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

1

High-throughput

0.611

High

169257

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

2

2

High-throughput

0.611

High

139433

PESC
Pescadillo homolog

3

2

High-throughput

0.609

High

169249

BOP1
Ribosome biogenesis protein BOP1

3

9

High-throughput

0.609

High

169260

DDX51
ATP-dependent RNA helicase DDX51

3

2

High-throughput

0.609

High

169265

SENP5
Sentrin-specific protease 5

3

1

High-throughput

0.609

High

169266

ZFP91
E3 ubiquitin-protein ligase ZFP91

3

5

High-throughput

0.609

High

169270

WDR12
Ribosome biogenesis protein WDR12

3

9

High-throughput

0.609

High

169274

E41L5
Band 4.1-like protein 5

3

6

High-throughput

0.609

High

169275

PRD10
PR domain zinc finger protein 10

3

6

High-throughput

0.609

High

169281

ZBT21
Zinc finger and BTB domain-containing protein 21

3

3

High-throughput

0.609

High

169287

ASB1
Ankyrin repeat and SOCS box protein 1

3

2

High-throughput

0.609

High

169288

TF3C3
General transcription factor 3C polypeptide 3

3

11

High-throughput

0.609

High

169267

TSNA1
t-SNARE domain-containing protein 1

3

2

High-throughput

0.599

High

169229

CBX6
Chromobox protein homolog 6

2

1

High-throughput

0.558

High

169233

H15
Histone H1.5

2

5

High-throughput

0.549

High

169232

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.541

High

169223

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

3

High-throughput

0.536

High

169228

MYO1D
Unconventional myosin-Id

1

4

High-throughput

0.536

High

169230

FBSP1
F-box/SPRY domain-containing protein 1

1

7

High-throughput

0.536

High

169283

MYO5B
Unconventional myosin-Vb

1

2

High-throughput

0.536

High

169286

MYO5A
Unconventional myosin-Va

1

2

High-throughput

0.536

High

169247

DNJC3
DnaJ homolog subfamily C member 3

1

20

High-throughput

0.515

High

169285

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

169237

MYH9
Myosin-9

1

0

High-throughput

0.493

High

169242

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.493

High

169251

PLEC
Plectin

1

0

High-throughput

0.493

High

169248

BYST
Bystin

1

0

High-throughput

0.493

High

169284

CHM2B
Charged multivesicular body protein 2b

1

4

High-throughput

0.479

High

169234

H12
Histone H1.2

1

5

High-throughput

0.470

High

169244

H11
Histone H1.1

1

5

High-throughput

0.470

High

169252

H31T
Histone H3.1t

1

4

High-throughput

0.470

High

169253

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.470

High

169264

H2B1H
Histone H2B type 1-H

1

5

High-throughput

0.470

High

169225

GTPB6
Putative GTP-binding protein 6

1

0

High-throughput

0.458

High

169238

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

169239

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

169276

RIC8B
Chaperone Ric-8B

1

0

High-throughput

0.458

High

169231

H14
Histone H1.4

1

5

High-throughput

0.437

High

169235

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.437

High

48184

A0AVG3
t-SNARE domain containing 1

1

2

High-throughput

0.407

High

169254

SGO2
Shugoshin 2

3

0

High-throughput

0.347

High

169263

TF3C2
General transcription factor 3C polypeptide 2

3

0

High-throughput

0.347

High

169269

RM20
Large ribosomal subunit protein bL20m

3

0

High-throughput

0.347

High

169273

RM44
Large ribosomal subunit protein mL44

3

0

High-throughput

0.347

High

169279

NOP53
Ribosome biogenesis protein NOP53

3

0

High-throughput

0.347

High

169245

TF3C1
General transcription factor 3C polypeptide 1

2

0

High-throughput

0.318

High

169255

RM21
Large ribosomal subunit protein bL21m

2

0

High-throughput

0.318

High

169278

OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial

1

0

High-throughput

0.279

Low

69866

ERI2
ERI1 exoribonuclease 2

1

0

High-throughput

0.269

Low

169224

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.249

Low

169243

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.249

Low

169261

RM43
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

169262

FBX30
F-box only protein 30

1

0

High-throughput

0.249

Low

169289

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025