HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: S10A1 (P23297)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 94
+	Hs
		169242 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A2_HUMAN (1-90): 1.74e-31: 107: 52.22
+	Hs
		169226 MDM4_HUMAN (1-490): 0: 692: 100.00		S100B_HUMAN (3-93): 1.37e-29: 102: 58.24
+	Hs
		169246 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A5_HUMAN (1-94): 8.03e-25: 90.6: 45.75
+	Hs
		615210 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A1_HUMAN (1-94): 9.45e-38: 123: 100.00
+	Hs
		962851 MDM2_HUMAN (2-488): 0: 554: 31.56		HORN_HUMAN (1-88): 6.3e-32: 118: 35.23
+	Hs
		642935 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A4_HUMAN (1-90): 5.06e-32: 109: 51.11
+	Hs
		661229 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A2_HUMAN (1-90): 1.74e-31: 107: 52.22
+	Hs
		380767 MDM2_HUMAN (2-488): 0: 554: 31.56		S100B_HUMAN (3-93): 1.37e-29: 102: 58.24
+	Hs
		416609 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A6_HUMAN (1-88): 1.92e-26: 94.5: 44.32