HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: S10A5 (P33763)
Protein S100-A5 (Protein S-100D) (S100 calcium-binding protein A5)
Gene: S100A5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 92
+	Hs
		169240 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A1_HUMAN (1-91): 7.55e-35: 116: 43.62
+	Hs
		169242 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A2_HUMAN (1-87): 2.13e-29: 102: 51.11
+	Hs
		169226 MDM4_HUMAN (1-490): 0: 692: 100.00		S100B_HUMAN (3-90): 1.67e-27: 97.2: 39.56
+	Hs
		615210 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A1_HUMAN (1-91): 7.55e-35: 116: 43.62
+	Hs
		962851 MDM2_HUMAN (2-488): 0: 554: 31.56		HORN_HUMAN (1-90): 8.06e-30: 112: 27.96
+	Hs
		642935 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A4_HUMAN (1-87): 2.38e-30: 104: 51.11
+	Hs
		661229 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A2_HUMAN (1-87): 2.13e-29: 102: 51.11
+	Hs
		380767 MDM2_HUMAN (2-488): 0: 554: 31.56		S100B_HUMAN (3-90): 1.67e-27: 97.2: 39.56
+	Hs
		416609 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A6_HUMAN (1-87): 4.42e-27: 96: 52.27