HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: TRI46 (Q7Z4K8)
Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein)
Gene: TRIM46

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 759
+	Hs
		962841 MDM2_HUMAN (2-488): 0: 554: 31.56		TRI46_HUMAN (1-759): 0: 559: 100.00
+	Hs
		169305 MDM4_HUMAN (1-490): 0: 692: 100.00		TRI55_HUMAN (14-428): 1.43e-105: 335: 24.58
+	Hs
		962960 MDM2_HUMAN (2-488): 0: 554: 31.56		TRIM9_HUMAN (24-744): 1.72e-124: 390: 21.32
+	Hs
		962830 MDM2_HUMAN (2-488): 0: 554: 31.56		TRI67_HUMAN (27-744): 1.48e-106: 345: 19.62
+	Hs
		962961 MDM2_HUMAN (2-488): 0: 554: 31.56		TRIM4_HUMAN (25-149): 3.02e-30: 127: 16.80
+	Hs
		536785 MDM2_HUMAN (2-488): 0: 554: 31.56		TRI27_HUMAN (19-149): 3.94e-25: 112: 21.32