HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	29021135, 29129908, 34079125, 32677374, 35332266, 36098557, 36430693, 37075063, 21164480
Identification Methods	affinity chromatography technology, proximity labelling technology, unspecified method, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 136
+	Hs
		170333 TIF1A_HUMAN (1-1050): 0: 590: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		935372 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		935268 TRI36_HUMAN (41-404): 8.63e-70: 249: 16.84		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		935066 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086253 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		584928 RO52_HUMAN (114-485): 2.09e-64: 227: 12.67		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		668595 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		668778 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		935347 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		952683 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		935364 ZMYD8_HUMAN (740-1004): 2.24e-45: 180: 26.30		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		828415 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		934725 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1029482 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952312 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		935346 BAZ2B_HUMAN (828-999): 5.78e-16: 85.5: 29.74		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		934702 BPTF_HUMAN (879-1002): 2.37e-12: 73.9: 40.00		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Dm
		356121 NU301_DROME (839-1004): 9.76e-13: 75.1: 31.95		H3_DROME (1-136): 6.5e-61: 185: 99.27
+	Hs
		952300 BPTF_HUMAN (879-1002): 2.37e-12: 73.9: 40.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		828212 BPTF_HUMAN (879-1002): 2.37e-12: 73.9: 40.00		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00