HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 3230
+	Hs
		1170076 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SRCAP_HUMAN (1-3230): 0: 1210: 100.00
+	Hs
		1172508 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		Q6ZTM8_HUMAN (1386-1897): 0: 589: 97.85
+	Hs
		1059944 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		229523 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Dm
		1363799 Q9VDK5_DROME (9-1024): 2.35e-103: 352: 21.78		INO80_DROME (1949-2507): 2.43e-78: 291: 22.83
+	Mm
		101401 F8VPM0_MOUSE (278-1011): 2.12e-68: 253: 16.87		SMCA5_MOUSE (2003-2357): 1.11e-90: 323: 28.77
+	Mm
		1265217 BAZ2A_MOUSE (278-1011): 2.8e-68: 253: 16.87		SMCA5_MOUSE (2003-2357): 1.11e-90: 323: 28.77
+	Mm
		70929 EP300_MOUSE (376-1001): 3.38e-64: 240: 15.94		CHD4_MOUSE (1959-2647): 3.91e-88: 324: 19.80
+	Hs
		847115 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		151520 TRIM1_HUMAN (31-471): 1.64e-70: 252: 14.95		CHD2_HUMAN (2039-2386): 6.82e-78: 291: 27.90
+	Hs
		846897 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SMCA2_HUMAN (1477-1770): 8.82e-09: 63.8: 11.91
+	Hs
		668690 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		1059928 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		229519 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Dm
		1364083 Q9VLR7_DROME (9-408): 5.41e-58: 218: 18.14		INO80_DROME (1949-2507): 2.43e-78: 291: 22.83
+	Hs
		668993 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		847041 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		846837 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SMCA2_HUMAN (1477-1770): 8.82e-09: 63.8: 11.91
+	Hs
		668914 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Hs
		847113 ZMYD8_HUMAN (740-1004): 2.24e-45: 180: 26.30		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22