HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35803934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 577
+	Hs
		127941 TIF1A_HUMAN (1-1050): 0: 590: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		128021 RO52_HUMAN (114-485): 2.09e-64: 227: 12.67		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1102503 LIN41_HUMAN (66-430): 5.44e-55: 208: 18.29		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		128163 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1029957 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1283867 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1273099 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		1310873 TRI56_HUMAN (42-615): 2.82e-57: 214: 15.29		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1294236 TRI56_HUMAN (42-615): 2.82e-57: 214: 15.29		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		668890 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1071988 TRI56_HUMAN (42-615): 2.82e-57: 214: 15.29		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		668704 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		1030079 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1029737 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1029450 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17