Protein: CLD1
Claudin-1 (Senescence-associated epithelial membrane protein)

Gene: CLD1, CLDN1
Organism: Homo sapiens
Interactions: 25
UniProt ID: O95832

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005198 - structural molecule activity
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0007155 - cell adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

194636

CLD3
Claudin-3

1

6

Small-scale

0.618

High

348831

CD69
Early activation antigen CD69

2

6

High-throughput

0.606

High

348835

T179B
Transmembrane protein 179B

2

1

High-throughput

0.606

High

348838

FNDC9
Fibronectin type III domain-containing protein 9

2

2

High-throughput

0.606

High

348839

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

3

High-throughput

0.606

High

348824

RASK
GTPase KRas

2

4

High-throughput

0.584

High

348826

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

348840

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

2

1

High-throughput

0.553

High

348836

INADL
InaD-like protein

1

7

Small-scale

0.527

High

348843

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.518

High

325373

ZO3
Tight junction protein ZO-3

1

20

Small-scale

0.501

High

348832

ZO1
Tight junction protein 1

1

20

Small-scale

0.501

High

348841

ZO2
Tight junction protein 2

1

20

Small-scale

0.501

High

348823

RASH
GTPase HRas

1

3

High-throughput

0.479

High

348830

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

348842

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

189369

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

348829

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

348833

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

348834

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

348825

TACD2
Tumor-associated calcium signal transducer 2

1

2

Small-scale

0.445

High

348828

CD81
CD81 antigen

1

6

High-throughput

0.445

High

348837

LNX1
E3 ubiquitin-protein ligase LNX

1

7

Small-scale

0.439

High

348827

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

259269

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025