Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 28966723, 16890161, 19107203, 20128690, 22682247, 23959799, 23892894, 24976009
Identification Methods affinity chromatography technology, far western blotting, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0031410 - cytoplasmic vesicle
GO:0042803 - protein homodimerization activity
GO:0060070 - canonical Wnt signaling pathway
GO:1990909 - Wnt signalosome
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 862
Hs

1 1613
+ Mm
+ Hs
+ Mm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024