Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1
Interactor 2: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.92 | 0.60 | 0.746 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28966723, 16890161, 19107203, 20128690, 22682247, 23959799, 23892894, 24976009 |
Identification Methods | affinity chromatography technology, far western blotting, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005886 - plasma membrane GO:0031410 - cytoplasmic vesicle GO:0042803 - protein homodimerization activity GO:0060070 - canonical Wnt signaling pathway GO:1990909 - Wnt signalosome |
Homologous interactions | 5 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024