HitPredict

Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22682247, 17510365
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 685
+	Hs
		475447 RGS2_HUMAN (24-219): 7.08e-52: 182: 22.28		UBC_HUMAN (1-685): 0: 846: 100.00
+	Rn
		834948 RGS7_RAT (29-221): 6.82e-63: 221: 18.37		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		476985 RGS19_MOUSE (18-219): 7.06e-52: 182: 25.36		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		69933 B1H233_RAT (27-217): 1.41e-51: 182: 22.80		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		397845 RGS3_HUMAN (62-218): 2.82e-46: 182: 29.94		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69