Protein: PACC1
Proton-activated chloride channel (PAC) (hPAC) (Acid-sensitive outwardly-rectifying anion channel) (ASOR) (Proton-activated outwardly rectifying anion channel) (PAORAC) (Transmembrane protein 206) (hTMEM206)

Gene: PACC1
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9H813

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006821 - chloride transport
GO:0009986 - cell surface
GO:0034707 - chloride channel complex
GO:0061797 - pH-gated chloride channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1313985

TM147
BOS complex subunit TMEM147

4

0

High-throughput

0.669

High

871967

AT12A
Potassium-transporting ATPase alpha chain 2

2

1

High-throughput

0.628

High

897953

RAP1B
Ras-related protein Rap-1b

2

1

High-throughput

0.628

High

1047812

CKAP5
Cytoskeleton-associated protein 5

2

2

High-throughput

0.628

High

354767

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

1

High-throughput

0.611

High

172603

GNPAT
Dihydroxyacetone phosphate acyltransferase

2

0

High-throughput

0.602

High

311117

MPZL1
Myelin protein zero-like protein 1

2

0

High-throughput

0.602

High

841524

KNTC1
Kinetochore-associated protein 1

2

0

High-throughput

0.602

High

1079439

VAMP3
Vesicle-associated membrane protein 3

2

0

High-throughput

0.602

High

1139213

DAB2P
Disabled homolog 2-interacting protein

2

0

High-throughput

0.602

High

1239123

MIGA1
Mitoguardin 1

2

0

High-throughput

0.602

High

1291433

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.602

High

1312337

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

2

0

High-throughput

0.602

High

1319359

TTYH3
Protein tweety homolog 3

2

0

High-throughput

0.602

High

1333283

RAB9B
Ras-related protein Rab-9B

2

0

High-throughput

0.602

High

982773

PLP2
Proteolipid protein 2

2

0

High-throughput

0.580

High

236456

RNBP6
Ran-binding protein 6

2

3

High-throughput

0.574

High

312391

IPO7
Importin-7

2

6

High-throughput

0.574

High

874592

XPO2
Exportin-2

2

6

High-throughput

0.574

High

1025691

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

3

High-throughput

0.574

High

1070039

PWP2
Periodic tryptophan protein 2 homolog

2

3

High-throughput

0.574

High

1136957

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

2

1

High-throughput

0.574

High

1173928

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

2

1

High-throughput

0.574

High

1183812

5MP2
eIF5-mimic protein 2

2

2

High-throughput

0.574

High

1299133

IPO9
Importin-9

2

6

High-throughput

0.574

High

1319216

XPO4
Exportin-4

2

1

High-throughput

0.574

High

1333284

EI2BG
Translation initiation factor eIF2B subunit gamma

2

1

High-throughput

0.574

High

1333291

EI2BD
Translation initiation factor eIF2B subunit delta

2

1

High-throughput

0.574

High

1333292

IPO11
Importin-11

2

6

High-throughput

0.574

High

1333293

XPO7
Exportin-7

2

2

High-throughput

0.574

High

1333295

WDR3
WD repeat-containing protein 3

2

1

High-throughput

0.574

High

1333298

RBGP1
Rab GTPase-activating protein 1

2

1

High-throughput

0.574

High

1333299

TNPO3
Transportin-3

2

4

High-throughput

0.574

High

1333301

5MP1
eIF5-mimic protein 1

2

2

High-throughput

0.574

High

155641

TNPO2
Transportin-2

2

5

High-throughput

0.558

High

1333297

PLLP
Plasmolipin

2

1

High-throughput

0.553

High

348927

RASN
GTPase NRas

1

1

High-throughput

0.536

High

530975

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.536

High

570893

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.536

High

798573

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.536

High

921727

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.536

High

958323

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

168279

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.513

High

178786

STX7
Syntaxin-7

1

0

High-throughput

0.513

High

776821

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.513

High

1053435

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.513

High

1170024

QSOX2
Sulfhydryl oxidase 2

1

0

High-throughput

0.513

High

834454

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.489

High

997466

VAC14
Protein VAC14 homolog

1

4

High-throughput

0.489

High

1273221

TNPO1
Transportin-1

1

5

High-throughput

0.489

High

1333280

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

1

High-throughput

0.489

High

1333282

AT131
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.489

High

616644

GLRA2
Glycine receptor subunit alpha-2

1

1

High-throughput

0.479

High

1114535

ZACN
Ligand-gated cation channel ZACN

1

3

High-throughput

0.479

High

1263275

5HT3C
5-hydroxytryptamine receptor 3C

1

2

High-throughput

0.479

High

127053

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

205993

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

488385

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.458

High

905562

TSN5
Tetraspanin-5

1

0

High-throughput

0.458

High

1165582

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

1

0

High-throughput

0.458

High

1254996

MCLN3
Mucolipin-3

1

0

High-throughput

0.458

High

1117740

Q4LE60
TNPO2 variant protein

1

5

High-throughput

0.407

High

298800

UFL1
E3 UFM1-protein ligase 1

2

0

High-throughput

0.328

High

315068

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.328

High

622839

COT2
COUP transcription factor 2

2

0

High-throughput

0.328

High

787571

MTOR
Serine/threonine-protein kinase mTOR

2

0

High-throughput

0.328

High

829135

PCY1A
Choline-phosphate cytidylyltransferase A

2

0

High-throughput

0.328

High

864263

CCHL
Holocytochrome c-type synthase

2

0

High-throughput

0.328

High

1066710

KIF14
Kinesin-like protein KIF14

2

0

High-throughput

0.328

High

1082540

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

0

High-throughput

0.328

High

1156518

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.328

High

1157533

MZT2B
Mitotic-spindle organizing protein 2B

2

0

High-throughput

0.328

High

1168084

THADA
tRNA

2

0

High-throughput

0.328

High

1190569

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.328

High

1198996

NOP9
Nucleolar protein 9

2

0

High-throughput

0.328

High

1234724

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.328

High

1236365

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

0

High-throughput

0.328

High

1253214

TBC15
TBC1 domain family member 15

2

0

High-throughput

0.328

High

1266560

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

0

High-throughput

0.328

High

1273400

GLMN
Glomulin

2

0

High-throughput

0.328

High

1282837

FAKD4
FAST kinase domain-containing protein 4

2

0

High-throughput

0.328

High

1284449

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

0

High-throughput

0.328

High

1290229

SAAL1
Protein SAAL1

2

0

High-throughput

0.328

High

1295026

CK5P3
CDK5 regulatory subunit-associated protein 3

2

0

High-throughput

0.328

High

1297896

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

2

0

High-throughput

0.328

High

1299373

RBM14
RNA-binding protein 14

2

0

High-throughput

0.328

High

1311275

GCP2
Gamma-tubulin complex component 2

2

0

High-throughput

0.328

High

1312189

DCNL5
DCN1-like protein 5

2

0

High-throughput

0.328

High

1327997

TM222
Transmembrane protein 222

2

0

High-throughput

0.328

High

1333279

ZWILC
Protein zwilch homolog

2

0

High-throughput

0.328

High

1333281

RDH14
Retinol dehydrogenase 14

2

0

High-throughput

0.328

High

1333285

F1142
Protein FAM114A2

2

0

High-throughput

0.328

High

1333287

TM38B
Trimeric intracellular cation channel type B

2

0

High-throughput

0.328

High

1333288

COMD3
COMM domain-containing protein 3

2

0

High-throughput

0.328

High

1333289

CS025
UPF0449 protein C19orf25

2

0

High-throughput

0.328

High

1333290

ARMX3
Armadillo repeat-containing X-linked protein 3

2

0

High-throughput

0.328

High

1333296

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.328

High

1333300

MTCH2
Mitochondrial carrier homolog 2

2

0

High-throughput

0.328

High

1117652

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1294710

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

242290

PRAF2
PRA1 family protein 2

1

0

High-throughput

0.279

Low

273987

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.279

Low

654789

CALX
Calnexin

1

0

High-throughput

0.279

Low

795051

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

880055

RRP1
Ribosomal RNA processing protein 1 homolog A

1

0

High-throughput

0.279

Low

1015949

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.279

Low

1152579

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

0

High-throughput

0.279

Low

1160335

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1170044

MMS22
Protein MMS22-like

1

0

High-throughput

0.279

Low

1218245

NNRD
ATP-dependent

1

0

High-throughput

0.279

Low

1224006

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1231590

GHDC
GH3 domain-containing protein

1

0

High-throughput

0.279

Low

1261584

STAG1
Cohesin subunit SA-1

1

0

High-throughput

0.279

Low

1294009

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.279

Low

1308607

CND3
Condensin complex subunit 3

1

0

High-throughput

0.279

Low

1333286

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.279

Low

1171738

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1240779

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.249

Low

1333294

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024