Protein: SO1B3
Solute carrier organic anion transporter family member 1B3 (Liver-specific organic anion transporter 2) (LST-2) (OATP1B3) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP-8) (Solute carrier family 21 member 8)

Gene: SO1B3, SLCO1B3
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q9NPD5

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005886 - plasma membrane
GO:0006805 - xenobiotic metabolic process
GO:0006811 - monoatomic ion transport
GO:0008514 - organic anion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446228

SO1B1
Solute carrier organic anion transporter family member 1B1

2

2

High-throughput

0.776

High

609814

LEG3
Galectin-3

2

4

High-throughput

0.601

High

1198281

FND3B
Fibronectin type III domain-containing protein 3B

2

2

High-throughput

0.549

High

732947

GASR
Gastrin/cholecystokinin type B receptor

1

1

Small-scale

0.501

High

1273971

DYM
Dymeclin

1

1

High-throughput

0.489

High

1287609

ADCK1
AarF domain-containing protein kinase 1

1

2

High-throughput

0.489

High

154537

PLPP1
Phospholipid phosphatase 1

1

1

High-throughput

0.445

High

154577

PLPP3
Phospholipid phosphatase 3

1

1

High-throughput

0.445

High

220541

CAH12
Carbonic anhydrase 12

1

1

High-throughput

0.445

High

299389

FLOT1
Flotillin-1

1

2

High-throughput

0.445

High

374215

RASN
GTPase NRas

1

9

High-throughput

0.445

High

418746

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

4

High-throughput

0.445

High

420709

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.445

High

420847

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.445

High

463233

YES
Tyrosine-protein kinase Yes

1

2

High-throughput

0.445

High

463784

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.445

High

467302

MDR1
ATP-dependent translocase ABCB1

1

1

High-throughput

0.445

High

476041

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

4

High-throughput

0.445

High

577899

PLAK
Junction plakoglobin

1

1

High-throughput

0.445

High

710898

EPHB2
Ephrin type-B receptor 2

1

4

High-throughput

0.445

High

774644

BASI
Basigin

1

3

High-throughput

0.445

High

787453

TGFR1
TGF-beta receptor type-1

1

2

High-throughput

0.445

High

931457

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

1

High-throughput

0.445

High

956613

RAB5B
Ras-related protein Rab-5B

1

4

High-throughput

0.445

High

982131

RAP1A
Ras-related protein Rap-1A

1

7

High-throughput

0.445

High

983588

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

High-throughput

0.445

High

984291

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.445

High

989384

VAMP2
Vesicle-associated membrane protein 2

1

2

High-throughput

0.445

High

989799

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

3

High-throughput

0.445

High

989880

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

4

High-throughput

0.445

High

1087305

STX4
Syntaxin-4

1

1

High-throughput

0.445

High

1101783

PTK7
Inactive tyrosine-protein kinase 7

1

3

High-throughput

0.445

High

1120827

DSG2
Desmoglein-2

1

1

High-throughput

0.445

High

1124923

FLOT2
Flotillin-2

1

2

High-throughput

0.445

High

1147441

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.445

High

1154754

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.445

High

1159867

OCLN
Occludin

1

2

High-throughput

0.445

High

1212307

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.445

High

1233508

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.445

High

1333121

AT11C
Phospholipid-transporting ATPase IG

1

5

High-throughput

0.445

High

1339289

RAI3
Retinoic acid-induced protein 3

1

1

High-throughput

0.445

High

1371970

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.445

High

1411414

CAB45
45 kDa calcium-binding protein

1

1

High-throughput

0.445

High

1433355

GOLP3
Golgi phosphoprotein 3

1

3

High-throughput

0.445

High

1439708

JPH1
Junctophilin-1

1

1

High-throughput

0.445

High

1446224

AT11B
Phospholipid-transporting ATPase IF

1

5

High-throughput

0.445

High

1446225

AT8A1
Phospholipid-transporting ATPase IA

1

4

High-throughput

0.445

High

1446226

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.445

High

124111

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.426

High

249062

NRP2
Neuropilin-2

1

0

High-throughput

0.426

High

467035

DAF
Complement decay-accelerating factor

1

0

High-throughput

0.426

High

562816

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.426

High

569221

CD59
CD59 glycoprotein

1

0

High-throughput

0.426

High

591375

CD44
CD44 antigen

1

0

High-throughput

0.426

High

604228

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.426

High

692269

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.426

High

720049

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.426

High

800573

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.426

High

846796

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.426

High

928817

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.426

High

1090013

LMAN2
Vesicular integral-membrane protein VIP36

1

0

High-throughput

0.426

High

1105248

S39A6
Zinc transporter ZIP6

1

0

High-throughput

0.426

High

1131463

RFTN1
Raftlin

1

0

High-throughput

0.426

High

1155272

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.426

High

1158787

SYPL1
Synaptophysin-like protein 1

1

0

High-throughput

0.426

High

1295571

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.426

High

1363276

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.426

High

1402468

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.426

High

1420725

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1446218

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.426

High

1446219

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.426

High

1446222

GBG12

1

0

High-throughput

0.426

High

127398

LEG8
Galectin-8

1

4

High-throughput

0.407

High

170977

CLGN
Calmegin

1

9

High-throughput

0.407

High

173407

XPO1
Exportin-1

1

6

High-throughput

0.407

High

219375

B4GA1
Beta-1,4-glucuronyltransferase 1

1

1

High-throughput

0.407

High

252546

SEP15
Selenoprotein F

1

2

High-throughput

0.407

High

334915

IPO7
Importin-7

1

8

High-throughput

0.407

High

336173

CNIH1
Protein cornichon homolog 1

1

2

High-throughput

0.407

High

699160

CALX
Calnexin

1

9

High-throughput

0.407

High

717613

PDIA3
Protein disulfide-isomerase A3

1

5

High-throughput

0.407

High

890166

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.407

High

934173

XPO2
Exportin-2

1

10

High-throughput

0.407

High

938627

PSA
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.407

High

1134397

IMB1
Importin subunit beta-1

1

4

High-throughput

0.407

High

1215369

DCAF8
DDB1- and CUL4-associated factor 8

1

4

High-throughput

0.407

High

1239829

MZT2B
Mitotic-spindle organizing protein 2B

1

1

High-throughput

0.407

High

1371010

TNPO1
Transportin-1

1

6

High-throughput

0.407

High

1382511

MALD3
MARVEL domain-containing protein 3

1

2

High-throughput

0.407

High

1404229

SEC62
Translocation protein SEC62

1

1

High-throughput

0.407

High

1432747

TMX1
Thioredoxin-related transmembrane protein 1

1

10

High-throughput

0.407

High

1432804

GCP60
Golgi resident protein GCP60

1

1

High-throughput

0.407

High

1446216

EI2BG
Translation initiation factor eIF2B subunit gamma

1

2

High-throughput

0.407

High

1446220

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

5

High-throughput

0.407

High

1446221

CNIH4
Protein cornichon homolog 4

1

2

High-throughput

0.407

High

1446223

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.407

High

1446227

TBL2
Transducin beta-like protein 2

1

3

High-throughput

0.407

High

732851

GLPK
Glycerol kinase

1

0

High-throughput

0.279

Low

977835

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.279

Low

904386

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

325604

YIF1A
Protein YIF1A

1

0

High-throughput

0.232

Low

828449

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.232

Low

1238692

TM214
Transmembrane protein 214

1

0

High-throughput

0.232

Low

1329735

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.232

Low

1395868

CLP1L
Lipid scramblase CLPTM1L

1

0

High-throughput

0.232

Low

1412539

GCP2
Gamma-tubulin complex component 2

1

0

High-throughput

0.232

Low

1419792

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.232

Low

1430882

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.232

Low

1439351

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.232

Low

1446217

F1142
Protein FAM114A2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025