HitPredict

Interactor 1: CETN3 (O15182)
Centrin-3
Gene: CETN3

Interactor 2: EFC11 (Q9BUY7)
EF-hand calcium-binding domain-containing protein 11
Gene: EFCAB11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~EF-hand_7, EF-hand_7~EF-hand_8
Common GO terms	GO:0005509 - calcium ion binding GO:0005815 - microtubule organizing center GO:0008017 - microtubule binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 167 Hs			1 163
+	Hs
		171125 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		CETN2_HUMAN (4-156): 1.37e-47: 154: 24.68
+	Hs
		1016740 CETN1_HUMAN (13-163): 2.24e-44: 145: 58.94		EFC11_HUMAN (1-163): 1.13e-68: 207: 100.00
+	Hs
		781592 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		EFC11_HUMAN (1-163): 1.13e-68: 207: 100.00
+	Gm
		1196117 Q84P28_SOYBN (4-166): 2.68e-50: 169: 28.14		Q84P28_SOYBN (4-161): 1.63e-45: 156: 21.38
+	At
		1104924 CDPK4_ARATH (1-166): 1.54e-46: 159: 29.41		CDPK4_ARATH (4-160): 5.93e-45: 155: 22.15
+	At
		1105900 CDPKB_ARATH (1-166): 3.52e-46: 158: 28.82		CDPKB_ARATH (4-160): 6.8e-45: 155: 22.15
+	Hs
		171115 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		CALM1_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171116 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		CALM2_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171117 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		CALM3_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		171132 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		CETN1_HUMAN (90-162): 2.14e-09: 55.4: 27.40
+	Hs
		781544 CETN1_HUMAN (13-163): 2.24e-44: 145: 58.94		CETN2_HUMAN (4-156): 1.37e-47: 154: 24.68
+	At
		989458 CDPK1_ARATH (1-166): 1.34e-46: 161: 26.47		CDPK1_ARATH (28-155): 1.82e-12: 66: 20.16
+	Hs
		483908 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		CALM1_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		483980 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		CALM2_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		484069 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		CALM3_HUMAN (3-86): 1.7e-11: 60.2: 21.18
+	Hs
		483903 CALM1_HUMAN (97-167): 7.16e-13: 64.1: 39.44		CALL3_HUMAN (3-86): 2.3e-10: 57.5: 21.18
+	Hs
		483976 CALM2_HUMAN (97-167): 7.16e-13: 64.1: 39.44		CALL3_HUMAN (3-86): 2.3e-10: 57.5: 21.18