Protein: PP12C
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)

Gene: PP12C, PPP1R12C
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9BZL4

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0004857 - enzyme inhibitor activity
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0017020 - myosin phosphatase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

244279

NUAK1
NUAK family SNF1-like kinase 1

2

6

Small-scale

0.789

High

1420040

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

2

18

Small-scale

0.757

High

171319

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

18

High-throughput

0.715

High

1420038

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

16

High-throughput

0.698

High

1420039

NUAK2
NUAK family SNF1-like kinase 2

2

6

High-throughput

0.694

High

968433

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

3

20

High-throughput

0.678

High

1420043

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.646

High

1420044

TBA8
Tubulin alpha-8 chain

1

11

High-throughput

0.621

High

331297

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.618

High

942864

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.618

High

1140809

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.618

High

1394002

SPF45
Splicing factor 45

3

3

High-throughput

0.616

High

635416

CO9A1

3

3

High-throughput

0.609

High

1229861

CYTSA
Cytospin-A

2

15

High-throughput

0.606

High

1274015

BHA09
Class A basic helix-loop-helix protein 9

2

6

High-throughput

0.606

High

1390968

THOC1
THO complex subunit 1

2

0

High-throughput

0.580

High

1420046

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.580

High

1395074

JPH4
Junctophilin-4

2

4

High-throughput

0.574

High

1014607

SMAD3
Mothers against decapentaplegic homolog 3

1

6

High-throughput

0.573

High

1420041

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

4

Small-scale

0.573

High

396886

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

967953

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

20

High-throughput

0.571

High

1250772

MPRIP
Myosin phosphatase Rho-interacting protein

2

20

Small-scale

0.566

High

1330077

USBP1
Harmonin-binding protein USHBP1

2

9

High-throughput

0.553

High

1330175

CC185
Coiled-coil domain-containing protein 185

2

5

High-throughput

0.553

High

541674

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.553

High

900142

FXR1
RNA-binding protein FXR1

1

10

High-throughput

0.541

High

900495

FXR2
RNA-binding protein FXR2

1

10

High-throughput

0.541

High

1056950

FMR1
Fragile X messenger ribonucleoprotein 1

1

10

High-throughput

0.541

High

1119782

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

1

17

Small-scale

0.523

High

998161

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.518

High

1405520

ZBT18
Zinc finger and BTB domain-containing protein 18

1

20

High-throughput

0.514

High

139746

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

8

High-throughput

0.508

High

903249

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

2

High-throughput

0.494

High

1246431

CORO6
Coronin-6

1

12

High-throughput

0.489

High

223310

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

630031

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

691400

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

730217

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

730868

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

786829

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

20

High-throughput

0.479

High

872722

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

966843

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

990698

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1049750

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1367208

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

184747

ATX7
Ataxin-7

1

12

High-throughput

0.464

High

564338

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

1326079

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.445

High

378180

TNFA
Tumor necrosis factor

1

2

High-throughput

0.437

High

1027731

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

7

High-throughput

0.437

High

1214192

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.437

High

430337

JUN
Transcription factor Jun

1

10

High-throughput

0.407

High

1420045

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.407

High

252909

EXOC3
Exocyst complex component 3

2

0

High-throughput

0.316

High

1420042

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

0

High-throughput

0.316

High

1420047

VATH
V-type proton ATPase subunit H

2

0

High-throughput

0.316

High

852023

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.299

High

1064022

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025