HitPredict

Interactor 1: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Interactor 2: GDC (P16260)
Solute carrier family 25 member 16 (Graves disease autoantigen) (GDA) (Graves disease carrier protein) (GDC) (Graves' didease protein) (hGP) (Mitochondrial solute carrier protein homolog)
Gene: SLC25A16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 332
+	Hs
		172204 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		SCMC3_HUMAN (36-331): 1.58e-94: 290: 32.43
+	Hs
		723393 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		SCMC3_HUMAN (36-331): 1.58e-94: 290: 32.43
+	Hs
		171926 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		ADT3_HUMAN (126-329): 1.21e-32: 124: 23.33
+	Hs
		723325 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		SCMC1_HUMAN (121-332): 4.69e-43: 156: 24.41
+	Hs
		781071 OPRX_HUMAN (3-352): 1.86e-70: 227: 23.18		SCMC1_HUMAN (121-332): 4.69e-43: 156: 24.41
+	Hs
		309897 OPRX_HUMAN (3-352): 1.86e-70: 227: 23.18		UCP5_HUMAN (91-332): 2.91e-37: 137: 24.10
+	Hs
		781065 OPRX_HUMAN (3-352): 1.86e-70: 227: 23.18		KMCP1_HUMAN (130-332): 5.64e-36: 133: 25.36
+	Hs
		428897 ADRB2_HUMAN (23-399): 3.66e-72: 233: 15.70		ADT3_HUMAN (126-329): 1.21e-32: 124: 23.33
+	Hs
		172233 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		TPC_HUMAN (40-210): 3.87e-18: 85.5: 32.43
+	Hs
		172049 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		SCMC2_HUMAN (240-332): 2.6e-14: 75.3: 24.73
+	Hs
		171925 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		ADT1_HUMAN (234-329): 5.54e-12: 67.2: 23.23
+	Hs
		429153 ADRB2_HUMAN (23-399): 3.66e-72: 233: 15.70		S2513_HUMAN (23-131): 7.69e-21: 95.3: 25.23
+	Hs
		723408 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		TPC_HUMAN (40-210): 3.87e-18: 85.5: 32.43
+	Hs
		723324 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		SCMC2_HUMAN (240-332): 2.6e-14: 75.3: 24.73
+	Hs
		518096 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		ADT1_HUMAN (234-329): 5.54e-12: 67.2: 23.23
+	Hs
		397232 ADRB2_HUMAN (23-399): 3.66e-72: 233: 15.70		ADT2_HUMAN (235-329): 2.35e-11: 65.3: 24.49
+	Hs
		798431 LPAR6_HUMAN (39-324): 2.15e-24: 104: 24.41		SCMC1_HUMAN (121-332): 4.69e-43: 156: 24.41
+	Hs
		518361 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		ADT3_HUMAN (126-329): 1.21e-32: 124: 23.33