HitPredict

Interactor 1: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Interactor 2: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 857
+	Hs
		708356 LPAR4_HUMAN (38-331): 1.5e-83: 261: 22.33		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708264 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708278 CXCR4_HUMAN (25-343): 3.18e-72: 231: 22.36		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708289 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708266 OPRX_HUMAN (3-352): 1.86e-70: 227: 23.18		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		598922 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		566331 CCR3_HUMAN (31-362): 2.93e-90: 278: 23.84		KPCA_HUMAN (367-850): 2.8e-118: 375: 14.94
+	Hs
		850652 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		KS6A3_HUMAN (477-818): 6.94e-81: 277: 21.05
+	Hs
		172234 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		NEK6_HUMAN (525-782): 3.1e-21: 97.4: 30.52
+	Hs
		1031129 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		M3K4_HUMAN (530-795): 2.19e-22: 105: 27.47