HitPredict

Interactor 1: CASC3 (O15234)
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)
Gene: CASC3

Interactor 2: MAP7 (Q14244)
Ensconsin (Epithelial microtubule-associated protein of 115 kDa) (E-MAP-115) (Microtubule-associated protein 7) (MAP-7)
Gene: MAP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 749
+	Hs
		172851 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Hs
		1056910 MDC1_HUMAN (26-703): 5.64e-39: 157: 9.51		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57
+	Hs
		998710 MDC1_HUMAN (26-703): 5.64e-39: 157: 9.51		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Hs
		554303 MUC1_HUMAN (2-702): 4.1e-33: 139: 10.47		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Hs
		1170076 SRCAP_HUMAN (73-702): 2.54e-11: 69.5: 10.32		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57
+	Hs
		1172508 Q6ZTM8_HUMAN (120-598): 6.99e-11: 67.2: 8.55		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57
+	Hs
		203228 SYNJ1_HUMAN (26-427): 1.45e-09: 63.7: 9.26		ITSN1_HUMAN (212-627): 5.03e-37: 152: 14.29
+	Hs
		297818 K0754_HUMAN (50-430): 7.32e-19: 94.2: 9.71		AFAD_HUMAN (112-729): 1.82e-27: 121: 12.28
+	Hs
		1356429 PCLO_HUMAN (3-586): 4.63e-12: 72.2: 8.94		TNIK_HUMAN (31-501): 3.32e-24: 111: 14.14
+	Hs
		998826 SRCAP_HUMAN (73-702): 2.54e-11: 69.5: 10.32		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Dm
		113976 M9PB30_DROME (4-690): 3.38e-14: 79.1: 8.88		M9PB30_DROME (150-746): 4.79e-21: 101: 9.70
+	Hs
		965118 OBSCN_HUMAN (253-702): 8.6e-09: 61.4: 9.73		ANK2_HUMAN (65-618): 3.44e-25: 114: 12.28
+	Mm
		102652 G3X972_MOUSE (243-563): 3.33e-09: 62.5: 9.85		TNIK_MOUSE (31-493): 1.7e-22: 105: 13.52
+	Hs
		302263 SC31A_HUMAN (343-634): 4.46e-17: 87.9: 13.16		UBP8_HUMAN (345-637): 4.07e-10: 65.4: 14.51
+	Mm
		1351630 PCLO_MOUSE (2-694): 3.44e-10: 66: 9.07		PCLO_MOUSE (16-748): 9.71e-11: 67.8: 7.53
+	Hs
		1137771 OBSCN_HUMAN (253-702): 8.6e-09: 61.4: 9.73		TITIN_HUMAN (68-741): 1.24e-11: 70.9: 8.66