Protein: E2F8
Transcription factor E2F8 (E2F-8)

Gene: E2F8
Organism: Homo sapiens
Interactions: 44
UniProt ID: A0AVK6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

48301

E2F7
Transcription factor E2F7

1

17

Small-scale

0.665

High

48304

CHIP
E3 ubiquitin-protein ligase CHIP

2

1

High-throughput

0.606

High

48295

TTC33
Tetratricopeptide repeat protein 33

2

2

High-throughput

0.549

High

48287

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.549

High

48279

NEK4
Serine/threonine-protein kinase Nek4

1

2

High-throughput

0.536

High

48290

FHL3
Four and a half LIM domains protein 3

1

5

High-throughput

0.523

High

48285

EWS
RNA-binding protein EWS

1

0

High-throughput

0.518

High

48264

KLF11
Krueppel-like factor 11

1

11

High-throughput

0.515

High

48265

RASH
GTPase HRas

1

3

High-throughput

0.515

High

48276

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.515

High

48280

CASP6
Caspase-6

1

1

High-throughput

0.515

High

48293

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.515

High

48303

UBQL1
Ubiquilin-1

1

2

High-throughput

0.515

High

48266

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

48297

ZDH17
Palmitoyltransferase ZDHHC17

1

5

High-throughput

0.494

High

48298

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

4

High-throughput

0.494

High

48263

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

48267

GELS
Gelsolin

1

0

High-throughput

0.493

High

48268

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.493

High

48273

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

48275

HD
Huntingtin

1

0

High-throughput

0.493

High

48296

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.493

High

48300

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

48278

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.481

High

48262

NFIB
Nuclear factor 1 B-type

1

15

High-throughput

0.479

High

48269

NFIC
Nuclear factor 1 C-type

1

17

High-throughput

0.479

High

48271

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

48272

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

48274

CCNF
Cyclin-F

1

16

Small-scale

0.479

High

48277

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

48281

1433G
14-3-3 protein gamma

1

6

High-throughput

0.479

High

48283

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

48284

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

High-throughput

0.479

High

48286

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

48288

NFIA
Nuclear factor 1 A-type

1

16

High-throughput

0.479

High

48291

NFIX
Nuclear factor 1 X-type

1

17

High-throughput

0.479

High

48282

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

48294

IF5AL
Eukaryotic translation initiation factor 5A-1-like

1

1

High-throughput

0.437

High

48302

XPO7
Exportin-7

1

2

High-throughput

0.437

High

48289

IFRD2
Interferon-related developmental regulator 2

1

0

High-throughput

0.269

Low

48299

OR1M1
Olfactory receptor 1M1

1

0

High-throughput

0.269

Low

48270

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

48292

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

48305

Q9Y649
GW128

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025