HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: TET3 (O43151)
Methylcytosine dioxygenase TET3 (EC 1.14.11.80)
Gene: TET3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	23222540, 23353889
Identification Methods	pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006493 - protein O-linked glycosylation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 1795
+	Hs
		195821 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		TET3_HUMAN (1-1795): 0: 1509: 100.00
+	Hs
		174965 OGT1_HUMAN (1-1046): 0: 969: 100.00		TET2_HUMAN (1590-1795): 7.86e-58: 224: 49.29
+	Hs
		91449 OGT1_HUMAN (1-1046): 0: 969: 100.00		E7EQS8_HUMAN (1590-1795): 6.87e-58: 224: 49.29
+	Mm
		1117016 OGT1_MOUSE (1-1046): 0: 970: 99.62		TET2_MOUSE (1590-1795): 1.46e-51: 203: 41.71
+	Hs
		175056 OGT1_HUMAN (1-1046): 0: 969: 100.00		TET1_HUMAN (47-379): 1.56e-22: 108: 22.35
+	Hs
		174891 OGT1_HUMAN (1-1046): 0: 969: 100.00		MDC1_HUMAN (200-888): 2.9e-16: 87.8: 8.65
+	Hs
		175053 OGT1_HUMAN (1-1046): 0: 969: 100.00		KMT2C_HUMAN (15-636): 3.6e-13: 77.5: 9.92
+	Hs
		672833 CDC27_HUMAN (214-530): 4.3e-38: 156: 16.35		MDC1_HUMAN (200-888): 2.9e-16: 87.8: 8.65
+	Hs
		684921 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		TITIN_HUMAN (11-929): 1.13e-09: 66.3: 9.30
+	Hs
		684649 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		IF4G1_HUMAN (39-582): 8.3e-09: 63.2: 10.13