Protein: MYCB2
E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc)

Gene: MYCB2, MYCBP2
Organism: Homo sapiens
Interactions: 221
UniProt ID: O75592

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270563

FBSP1
F-box/SPRY domain-containing protein 1

7

16

Small-scale

0.749

High

270607

1433G
14-3-3 protein gamma

6

20

High-throughput

0.730

High

270691

FBXW7
F-box/WD repeat-containing protein 7

6

9

Small-scale

0.729

High

270618

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

270581

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.709

High

270610

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.694

High

270577

1433T
14-3-3 protein theta

4

20

Small-scale

0.689

High

270554

MYC
Myc proto-oncogene protein

3

6

Small-scale

0.675

High

270621

LG3BP
Galectin-3-binding protein

3

4

High-throughput

0.675

High

270611

SKP1
S-phase kinase-associated protein 1

3

8

Small-scale

0.667

High

270667

SKAP1
Src kinase-associated phosphoprotein 1

3

7

High-throughput

0.667

High

270708

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

3

1

Small-scale

0.660

High

270567

TDGF1
Protein Cripto

3

0

High-throughput

0.638

High

270602

SESN3
Sestrin-3

3

0

High-throughput

0.638

High

270744

CLC11
C-type lectin domain family 11 member A

3

0

High-throughput

0.638

High

270653

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

3

3

Small-scale

0.633

High

270555

PDGFB
Platelet-derived growth factor subunit B

2

1

High-throughput

0.628

High

270684

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

1

High-throughput

0.628

High

270714

TXNIP
Thioredoxin-interacting protein

2

4

High-throughput

0.628

High

270723

DOCK5
Dedicator of cytokinesis protein 5

2

5

High-throughput

0.628

High

270738

CTNA3
Catenin alpha-3

2

3

High-throughput

0.628

High

270580

EPHB2
Ephrin type-B receptor 2

2

3

High-throughput

0.618

High

270606

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.611

High

159695

CASQ2
Calsequestrin-2

2

1

High-throughput

0.611

High

270572

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

3

High-throughput

0.611

High

270608

1433E
14-3-3 protein epsilon

2

1

High-throughput

0.611

High

270711

CAD19
Cadherin-19

2

2

High-throughput

0.611

High

270741

HECD1
E3 ubiquitin-protein ligase HECTD1

2

15

High-throughput

0.611

High

270750

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

2

1

Small-scale

0.611

High

270596

STAT2
Signal transducer and activator of transcription 2

2

0

High-throughput

0.602

High

270617

GCYB1
Guanylate cyclase soluble subunit beta-1

2

0

High-throughput

0.602

High

270622

CETN1
Centrin-1

2

0

High-throughput

0.602

High

270699

PGBD1
PiggyBac transposable element-derived protein 1

2

0

High-throughput

0.602

High

270582

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

270593

TSC2
Tuberin

2

6

Small-scale

0.596

High

270612

UB2L3
Ubiquitin-conjugating enzyme E2 L3

2

20

Small-scale

0.595

High

270727

NGRN
Neugrin

2

0

High-throughput

0.585

High

270587

CCNF
Cyclin-F

2

8

High-throughput

0.584

High

270615

RAE1L
mRNA export factor RAE1

2

8

High-throughput

0.584

High

270571

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

5

High-throughput

0.576

High

270600

GDF10
Growth/differentiation factor 10

2

3

High-throughput

0.574

High

270669

DRC2
Dynein regulatory complex subunit 2

2

2

High-throughput

0.574

High

152755

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

9

High-throughput

0.541

High

270559

HS90B
Heat shock protein HSP 90-beta

1

10

High-throughput

0.541

High

270562

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

4

High-throughput

0.541

High

270574

COF1
Cofilin-1

1

2

High-throughput

0.541

High

270584

SPB6
Serpin B6

1

1

High-throughput

0.541

High

270601

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

3

High-throughput

0.541

High

270605

CD81
CD81 antigen

1

1

High-throughput

0.541

High

270627

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.541

High

270628

FHL3
Four and a half LIM domains protein 3

1

3

High-throughput

0.541

High

270629

BTG3
Protein BTG3

1

1

High-throughput

0.541

High

270642

TBR1
T-box brain protein 1

1

1

High-throughput

0.541

High

270654

TBC9B
TBC1 domain family member 9B

1

1

High-throughput

0.541

High

270664

PABP2
Polyadenylate-binding protein 2

1

2

High-throughput

0.541

High

270675

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.541

High

270685

RSPH1
Radial spoke head 1 homolog

1

4

High-throughput

0.541

High

270686

TITIN
Titin

1

9

High-throughput

0.541

High

270697

LCOR
Ligand-dependent corepressor

1

1

High-throughput

0.541

High

270722

ASB8
Ankyrin repeat and SOCS box protein 8

1

6

High-throughput

0.541

High

270729

AT132
Polyamine-transporting ATPase 13A2

1

2

Small-scale

0.541

High

270732

AATF
Protein AATF

1

1

High-throughput

0.541

High

270737

PUF60
Poly(U)-binding-splicing factor PUF60

1

6

High-throughput

0.541

High

270739

DP13A
DCC-interacting protein 13-alpha

1

1

High-throughput

0.541

High

71050

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.536

High

270548

SVIL
Supervillin

1

6

High-throughput

0.536

High

270549

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

270570

NR1D1
Nuclear receptor subfamily 1 group D member 1

1

2

Small-scale

0.536

High

270579

MAP4
Microtubule-associated protein 4

1

10

High-throughput

0.536

High

270597

PLK1
Serine/threonine-protein kinase PLK1

1

6

High-throughput

0.536

High

270599

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.536

High

270613

TBB4B
Tubulin beta-4B chain

1

11

High-throughput

0.536

High

270626

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

270633

ICAM4
Intercellular adhesion molecule 4

1

2

High-throughput

0.536

High

270634

CBX2
Chromobox protein homolog 2

1

3

High-throughput

0.536

High

270636

EEA1
Early endosome antigen 1

1

4

High-throughput

0.536

High

270644

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.536

High

270668

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

1

High-throughput

0.536

High

270682

CKAP2
Cytoskeleton-associated protein 2

1

1

High-throughput

0.536

High

270694

HDA11
Histone deacetylase 11

1

11

High-throughput

0.536

High

270696

HIPL1
HHIP-like protein 1

1

3

High-throughput

0.536

High

270721

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

270734

PCD10
Protocadherin-10

1

2

High-throughput

0.536

High

270748

PCDB6
Protocadherin beta-6

1

2

High-throughput

0.536

High

270749

PCDA3
Protocadherin alpha-3

1

2

High-throughput

0.536

High

270546

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.518

High

270553

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.518

High

270558

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.518

High

270590

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.518

High

270598

OAZ1
Ornithine decarboxylase antizyme 1

1

0

High-throughput

0.518

High

270643

FSCN1
Fascin

1

0

High-throughput

0.518

High

270704

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.518

High

270716

CUED2
CUE domain-containing protein 2

1

0

High-throughput

0.518

High

270735

PI4KB
Phosphatidylinositol 4-kinase beta

1

0

High-throughput

0.518

High

270595

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

12

High-throughput

0.515

High

270641

BAK
Bcl-2 homologous antagonist/killer

1

1

High-throughput

0.515

High

270679

WDR48
WD repeat-containing protein 48

1

11

High-throughput

0.515

High

181142

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

270588

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.513

High

270589

MMP13
Collagenase 3

1

0

High-throughput

0.513

High

270616

NDP
Norrin

1

0

High-throughput

0.513

High

270620

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

270638

TESK1
Dual specificity testis-specific protein kinase 1

1

0

High-throughput

0.513

High

270648

VP26B
Vacuolar protein sorting-associated protein 26B

1

0

High-throughput

0.513

High

270652

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

270659

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.513

High

270676

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

270678

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

270689

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

270693

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.513

High

270702

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

270703

CSRN1
Cysteine/serine-rich nuclear protein 1

1

0

High-throughput

0.513

High

270706

TLR10
Toll-like receptor 10

1

0

High-throughput

0.513

High

270707

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

270713

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.513

High

270733

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.513

High

270609

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.501

High

270614

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.501

High

270576

IBP6
Insulin-like growth factor-binding protein 6

1

1

High-throughput

0.494

High

270631

SPRL1
SPARC-like protein 1

1

1

High-throughput

0.494

High

270660

TBCD9
TBC1 domain family member 9

1

1

High-throughput

0.494

High

270674

SPRY3
SPRY domain-containing protein 3

1

3

High-throughput

0.494

High

270637

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.493

High

270573

IBP4
Insulin-like growth factor-binding protein 4

1

1

High-throughput

0.489

High

270591

TFPI2
Tissue factor pathway inhibitor 2

1

1

High-throughput

0.489

High

270603

INHBE
Inhibin beta E chain

1

2

High-throughput

0.489

High

270663

ALPK2
Alpha-protein kinase 2

1

7

High-throughput

0.489

High

270683

OIT3
Oncoprotein-induced transcript 3 protein

1

1

High-throughput

0.489

High

270718

CSTN2
Calsyntenin-2

1

2

High-throughput

0.489

High

116750

KIF2A
Kinesin-like protein KIF2A

1

4

Small-scale

0.479

High

123149

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.479

High

128950

PLK4
Serine/threonine-protein kinase PLK4

1

7

High-throughput

0.479

High

158591

RGS12
Regulator of G-protein signaling 12

1

2

Small-scale

0.479

High

160290

AURKA
Aurora kinase A

1

9

High-throughput

0.479

High

204830

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

231920

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

270547

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

7

High-throughput

0.479

High

270550

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

270552

NSD2
Histone-lysine N-methyltransferase NSD2

1

8

Small-scale

0.479

High

270557

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

270561

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

270564

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

19

High-throughput

0.479

High

270565

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

270568

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

270578

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

270583

NOS2
Nitric oxide synthase, inducible

1

1

High-throughput

0.479

High

270585

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

270586

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.479

High

270594

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.479

High

270619

UBE3A
Ubiquitin-protein ligase E3A

1

16

Small-scale

0.479

High

270623

STK3
Serine/threonine-protein kinase 3

1

9

Small-scale

0.479

High

270624

HDAC1
Histone deacetylase 1

1

6

High-throughput

0.479

High

270625

CUL3
Cullin-3

1

20

High-throughput

0.479

High

270630

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

9

High-throughput

0.479

High

270635

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

270639

CRY1
Cryptochrome-1

1

1

High-throughput

0.479

High

270640

RBBP7
Histone-binding protein RBBP7

1

6

High-throughput

0.479

High

270645

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

270647

CRY2
Cryptochrome-2

1

1

High-throughput

0.479

High

270655

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.479

High

270661

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

270662

DNJB7
DnaJ homolog subfamily B member 7

1

5

High-throughput

0.479

High

270670

LIRA3
Leukocyte immunoglobulin-like receptor subfamily A member 3

1

3

High-throughput

0.479

High

270671

SIR6
NAD-dependent protein deacylase sirtuin-6

1

8

High-throughput

0.479

High

270672

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

270677

COP1
E3 ubiquitin-protein ligase COP1

1

18

High-throughput

0.479

High

270681

LNX1
E3 ubiquitin-protein ligase LNX

1

5

Small-scale

0.479

High

270687

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

270688

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

270690

ATOH1
Transcription factor ATOH1

1

4

Small-scale

0.479

High

270692

PF21A
PHD finger protein 21A

1

2

High-throughput

0.479

High

270698

NEUL4
Neuralized-like protein 4

1

3

High-throughput

0.479

High

270705

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.479

High

270709

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

270710

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

270715

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

270719

DEFI6
Differentially expressed in FDCP 6 homolog

1

7

High-throughput

0.479

High

270720

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

270724

ECT2
Protein ECT2

1

5

High-throughput

0.479

High

270726

MYO10
Unconventional myosin-X

1

1

Small-scale

0.479

High

270728

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

270730

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

270736

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

270740

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

270742

CC14A
Dual specificity protein phosphatase CDC14A

1

8

High-throughput

0.479

High

270743

FAF1
FAS-associated factor 1

1

5

High-throughput

0.479

High

270746

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

9

Small-scale

0.479

High

270575

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

270632

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

270646

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.458

High

270666

SERC5
Serine incorporator 5

1

0

Small-scale

0.458

High

270566

CLUS
Clusterin

1

1

High-throughput

0.457

High

270731

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.457

High

120774

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.445

High

270569

VINC
Vinculin

1

4

High-throughput

0.445

High

270665

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

2

High-throughput

0.445

High

270701

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.445

High

270717

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

9

High-throughput

0.445

High

100139

F6VUV4
Dehydrogenase/reductase 4 like 2

1

1

High-throughput

0.439

High

270695

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

270551

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

270650

CD158
Coiled-coil domain-containing protein 158

1

3

High-throughput

0.437

High

270745

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

270752

ICOS
Inducible T-cell costimulator

1

0

Small-scale

0.426

High

270604

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

270656

DR4L2
Dehydrogenase/reductase SDR family member 4-like 2

1

1

High-throughput

0.417

High

270592

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

270700

Q96KY9
CDH19 protein

1

3

High-throughput

0.407

High

270658

ACP7
Acid phosphatase type 7

2

0

High-throughput

0.324

High

270751

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.282

High

270556

C1QB
Complement C1q subcomponent subunit B

1

0

High-throughput

0.279

Low

270560

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.279

Low

270649

PLA1A
Phospholipase A1 member A

1

0

High-throughput

0.279

Low

270651

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

270657

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

270673

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

270712

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

270747

INSL6
Insulin-like peptide INSL6

1

0

High-throughput

0.279

Low

63261

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.249

Low

270680

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

270725

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024