HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32994395
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TPR_1~TPR_1, TPR_1~TPR_6, TPR_1~TPR_11, TPR_11~TPR_6, TPR_1~TPR_12, TPR_1~TPR_8
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 457
+	Hs
		174814 OGT1_HUMAN (1-1046): 0: 969: 100.00		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		174884 OGT1_HUMAN (1-1046): 0: 969: 100.00		FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23
+	Hs
		174661 OGT1_HUMAN (1-1046): 0: 969: 100.00		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		175098 OGT1_HUMAN (1-1046): 0: 969: 100.00		FKB10_HUMAN (134-285): 5.25e-13: 72.9: 20.51
+	Hs
		972498 IFT88_HUMAN (1-632): 7.1e-52: 198: 14.75		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		684691 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		297056 TOM70_HUMAN (352-634): 3.11e-15: 82.3: 12.06		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		684646 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		684824 CTR9_HUMAN (1-638): 1.09e-48: 190: 12.97		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		118697 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		684718 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23
+	Hs
		300062 PRP6_HUMAN (1-275): 6.86e-21: 101: 15.90		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		1012412 TMTC1_HUMAN (1-246): 2.18e-24: 112: 18.80		Q0VDC6_HUMAN (151-247): 5.97e-21: 90.6: 26.73
+	Hs
		645855 TTC13_HUMAN (1-188): 2.01e-20: 99.6: 18.62		FKBP2_HUMAN (153-255): 1.29e-23: 98: 27.52
+	Hs
		684432 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684975 DNJC7_HUMAN (7-170): 2.97e-17: 88.3: 14.12		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Dm
		817472 Q9VPN5_DROME (228-554): 2.71e-14: 78.8: 14.63		FKB12_DROME (153-247): 2.5e-20: 87.6: 26.26