HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34434118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0019899 - enzyme binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 435
+	Hs
		573758 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		570547 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98
+	Hs
		1020095 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		983497 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTN12_HUMAN (24-314): 1e-122: 376: 33.55
+	Hs
		489979 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		577031 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRA_HUMAN (12-278): 9.1e-105: 330: 31.62
+	Hs
		242807 TRI13_HUMAN (1-97): 1.22e-14: 78.2: 40.21		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		617053 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRE_HUMAN (3-278): 1.26e-92: 295: 26.71
+	Hs
		570562 SPRY4_HUMAN (486-660): 1.38e-18: 86.7: 28.65		PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98
+	Hs
		640245 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		PTN3_HUMAN (3-275): 1.72e-49: 182: 36.43
+	Hs
		1069936 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRK_HUMAN (6-279): 1.27e-61: 218: 25.18
+	Hs
		796414 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTN9_HUMAN (20-279): 3.35e-52: 186: 39.21
+	Hs
		985981 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTN11_HUMAN (39-274): 7.78e-49: 177: 38.80
+	Hs
		986025 FSD1_HUMAN (216-666): 4.93e-89: 288: 27.35		PTN11_HUMAN (39-274): 7.78e-49: 177: 38.80
+	Hs
		640263 TRI41_HUMAN (1-655): 3.11e-77: 260: 13.81		PTN3_HUMAN (3-275): 1.72e-49: 182: 36.43
+	Hs
		617169 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRZ_HUMAN (288-435): 4.77e-23: 104: 11.66
+	Hs
		617121 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46