Protein: IMA6
Importin subunit alpha-6 (Karyopherin subunit alpha-5)

Gene: IMA6, KPNA5
Organism: Homo sapiens
Interactions: 81
UniProt ID: O15131

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
GO:0006607 - NLS-bearing protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168678

NUP50
Nuclear pore complex protein Nup50

7

20

High-throughput

0.968

High

168660

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

5

10

High-throughput

0.718

High

168628

IMA5
Importin subunit alpha-5

1

7

High-throughput

0.691

High

168637

IMB1
Importin subunit beta-1

1

20

High-throughput

0.691

High

168646

SPOPL
Speckle-type POZ protein-like

3

7

High-throughput

0.675

High

168601

MCES
mRNA cap guanine-N7 methyltransferase

2

5

High-throughput

0.628

High

168602

SPOP
Speckle-type POZ protein

2

8

Small-scale

0.614

High

168624

CDN1B
Cyclin-dependent kinase inhibitor 1B

2

8

Small-scale

0.611

High

168636

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

20

Small-scale

0.611

High

168675

KBTB4
Kelch repeat and BTB domain-containing protein 4

3

6

Small-scale

0.609

High

168614

CFTR
Cystic fibrosis transmembrane conductance regulator

2

4

High-throughput

0.608

High

168611

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

6

High-throughput

0.606

High

168617

LMNB1
Lamin-B1

2

12

High-throughput

0.606

High

168622

MLH1
DNA mismatch repair protein Mlh1

2

3

High-throughput

0.606

High

168623

RAD52
DNA repair protein RAD52 homolog

2

1

High-throughput

0.606

High

168630

PO6F2
POU domain, class 6, transcription factor 2

2

11

High-throughput

0.606

High

168645

ZN326
DBIRD complex subunit ZNF326

2

3

High-throughput

0.606

High

168651

ATOSB
Atos homolog protein B

2

1

High-throughput

0.606

High

168661

KAT5
Histone acetyltransferase KAT5

2

7

High-throughput

0.606

High

168662

DCPS
m7GpppX diphosphatase

2

2

High-throughput

0.606

High

168667

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

5

High-throughput

0.606

High

168672

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

7

High-throughput

0.606

High

168627

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.586

High

168615

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

2

High-throughput

0.584

High

168650

MEPCE
7SK snRNA methylphosphate capping enzyme

2

6

High-throughput

0.584

High

168641

NRF1
Nuclear respiratory factor 1

2

0

High-throughput

0.580

High

168652

SEN54
tRNA-splicing endonuclease subunit Sen54

2

0

High-throughput

0.580

High

168658

SR1IP
Protein SREK1IP1

2

3

High-throughput

0.574

High

168644

LARP7
La-related protein 7

2

7

Small-scale

0.571

High

168616

WT1
Wilms tumor protein

1

9

High-throughput

0.541

High

126412

FOXE1
Forkhead box protein E1

1

5

High-throughput

0.536

High

133237

NOP56
Nucleolar protein 56

1

12

High-throughput

0.536

High

168604

MCE1
mRNA-capping enzyme

1

4

High-throughput

0.536

High

168626

NU153
Nuclear pore complex protein Nup153

1

20

High-throughput

0.536

High

168634

CUL3
Cullin-3

1

13

High-throughput

0.536

High

168635

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

13

High-throughput

0.536

High

168647

NIPBL
Nipped-B-like protein

1

4

High-throughput

0.536

High

168653

RBM45
RNA-binding protein 45

1

1

High-throughput

0.536

High

168654

KLHL7
Kelch-like protein 7

1

3

High-throughput

0.536

High

168656

NOPC1
NOP protein chaperone 1

1

2

High-throughput

0.536

High

168665

MTA3
Metastasis-associated protein MTA3

1

11

High-throughput

0.536

High

168666

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

11

High-throughput

0.536

High

168669

ADNP
Activity-dependent neuroprotector homeobox protein

1

3

High-throughput

0.536

High

168671

EAF6
Chromatin modification-related protein MEAF6

1

2

High-throughput

0.536

High

168673

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

20

High-throughput

0.536

High

168676

LYAR
Cell growth-regulating nucleolar protein

1

4

High-throughput

0.536

High

168677

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

0

High-throughput

0.513

High

168621

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

11

High-throughput

0.508

High

168619

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

14

Small-scale

0.501

High

168631

RBBP4
Histone-binding protein RBBP4

1

10

Small-scale

0.501

High

168639

TWST1
Twist-related protein 1

1

2

Small-scale

0.501

High

168642

HIF1A
Hypoxia-inducible factor 1-alpha

1

13

Small-scale

0.501

High

168664

EPAS1
Endothelial PAS domain-containing protein 1

1

13

Small-scale

0.501

High

168674

BRMS1
Breast cancer metastasis-suppressor 1

1

0

Small-scale

0.486

High

168633

ATM
Serine-protein kinase ATM

1

6

Small-scale

0.481

High

168679

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

168603

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

168605

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

168606

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

10

Small-scale

0.479

High

168608

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

168609

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

12

High-throughput

0.479

High

168610

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

168612

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

168613

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.479

High

168620

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

168625

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

168629

H31
Histone H3.1

1

7

High-throughput

0.479

High

168632

SKP2
S-phase kinase-associated protein 2

1

3

Small-scale

0.479

High

168640

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

168643

CL16A
Protein CLEC16A

1

3

High-throughput

0.479

High

168655

SLX4
Structure-specific endonuclease subunit SLX4

1

9

High-throughput

0.479

High

168657

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

6

High-throughput

0.479

High

168659

P66B
Transcriptional repressor p66-beta

1

4

High-throughput

0.479

High

168663

PHB2
Prohibitin-2

1

5

Small-scale

0.479

High

168668

AICDA
Single-stranded DNA cytosine deaminase

1

5

Small-scale

0.479

High

168618

IL32
Interleukin-32

1

0

Small-scale

0.460

High

168607

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

0

High-throughput

0.458

High

168638

SF01
Splicing factor 1

1

5

High-throughput

0.457

High

168648

SYNE3
Nesprin-3

1

1

High-throughput

0.437

High

168649

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

168670

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High


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Last updated: 15 Jul 2024