HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	25207814, 20092282, 22613722
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 309
+	Hs
		175656 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		891012 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		930843 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		930896 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915227 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		890981 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		737885 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Hs
		905982 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PP1A_HUMAN (5-296): 0: 504: 46.51
+	Hs
		906010 TRI42_HUMAN (4-402): 2.29e-77: 263: 22.14		PP1A_HUMAN (5-296): 0: 504: 46.51
+	Hs
		890961 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		536746 TRI27_HUMAN (90-433): 1.46e-30: 128: 14.08		PP1G_HUMAN (7-306): 0: 505: 45.96