Protein: TIAR
Nucleolysin TIAR (TIA-1-related protein)

Gene: TIAR, TIAL1
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q01085

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478003

SNRPA
U1 small nuclear ribonucleoprotein A

3

19

High-throughput

0.858

High

726752

TIA1
Cytotoxic granule associated RNA binding protein TIA1

3

14

Small-scale

0.839

High

1029033

CELF4
CUGBP Elav-like family member 4

2

19

High-throughput

0.783

High

1028999

MBNL2
Muscleblind-like protein 2

2

0

High-throughput

0.742

High

1029001

RBPS2
RNA-binding protein with multiple splicing 2

2

0

High-throughput

0.742

High

1029051

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

0

High-throughput

0.742

High

691706

MK03
Mitogen-activated protein kinase 3

1

7

High-throughput

0.691

High

1028966

TIAR
Nucleolysin TIAR

1

15

Small-scale

0.665

High

1028983

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

19

Small-scale

0.665

High

1028990

ELAV1
ELAV-like protein 1

1

17

Small-scale

0.665

High

1029008

DZIP3
E3 ubiquitin-protein ligase DZIP3

3

3

High-throughput

0.657

High

703537

MK01
Mitogen-activated protein kinase 1

1

7

Small-scale

0.647

High

1028970

TROP
Trophinin

2

3

High-throughput

0.628

High

1029038

SAV1
Protein salvador homolog 1

2

6

High-throughput

0.628

High

1028973

TADBP
TAR DNA-binding protein 43

1

19

High-throughput

0.625

High

47973

RBM47
RNA-binding protein 47

1

16

High-throughput

0.618

High

157251

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.618

High

172707

XPO1
Exportin-1

1

5

High-throughput

0.618

High

400667

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.618

High

472655

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

550237

PABP1
Polyadenylate-binding protein 1

1

14

High-throughput

0.618

High

688229

TTP
mRNA decay activator protein ZFP36

1

4

High-throughput

0.618

High

713764

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

18

High-throughput

0.618

High

1028974

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.618

High

1028975

G3BP1
Ras GTPase-activating protein-binding protein 1

1

12

High-throughput

0.618

High

1029019

CELF1
CUGBP Elav-like family member 1

1

18

High-throughput

0.618

High

1029020

DAZL
Deleted in azoospermia-like

1

17

High-throughput

0.618

High

1029047

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.618

High

1029055

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

20

High-throughput

0.618

High

63186

VP37C
Vacuolar protein sorting-associated protein 37C

2

4

High-throughput

0.606

High

1028976

KLF1
Krueppel-like factor 1

2

2

High-throughput

0.606

High

1029024

FUBP1
Far upstream element-binding protein 1

2

20

High-throughput

0.606

High

1029028

QKI
KH domain-containing RNA-binding protein QKI

2

6

High-throughput

0.606

High

1029054

MAGD1
Melanoma-associated antigen D1

2

3

High-throughput

0.606

High

1029000

FA83H
Protein FAM83H

2

0

High-throughput

0.602

High

1028989

SF01
Splicing factor 1

1

6

High-throughput

0.590

High

371785

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.584

High

588485

RFA2
Replication protein A 32 kDa subunit

2

3

High-throughput

0.584

High

767976

RFA3
Replication protein A 14 kDa subunit

2

2

High-throughput

0.584

High

1028969

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1028987

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

1029009

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.580

High

1029046

PRR13
Proline-rich protein 13

2

0

High-throughput

0.580

High

1029050

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.580

High

395927

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

50325

F168B
Myelin-associated neurite-outgrowth inhibitor

2

1

High-throughput

0.553

High

1029005

LFG1
Protein lifeguard 1

2

1

High-throughput

0.553

High

1029013

MISSL
MAPK-interacting and spindle-stabilizing protein-like

2

2

High-throughput

0.553

High

1029016

F168A
Protein FAM168A

2

1

High-throughput

0.553

High

872206

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.536

High

1028978

CUL1
Cullin-1

1

20

High-throughput

0.536

High

1028979

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1028980

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1028981

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

1028982

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

1028991

NEDD8
Ubiquitin-like protein NEDD8

1

2

High-throughput

0.536

High

1029004

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.536

High

1029007

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1029010

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1029021

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.536

High

1029023

CUL5
Cullin-5

1

20

High-throughput

0.536

High

1029025

DCNL1
DCN1-like protein 1

1

3

High-throughput

0.536

High

1029041

MOV10
Helicase MOV-10

1

8

Small-scale

0.536

High

1029052

EMC9
ER membrane protein complex subunit 9

1

3

High-throughput

0.536

High

619747

VCAM1
Vascular cell adhesion protein 1

2

7

High-throughput

0.521

High

703928

DUS1
Dual specificity protein phosphatase 1

1

4

Small-scale

0.515

High

1028972

ILF3
Interleukin enhancer-binding factor 3

1

7

Small-scale

0.515

High

1029022

FUBP2
Far upstream element-binding protein 2

1

20

Small-scale

0.515

High

122752

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

1029015

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

1028996

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

1

0

High-throughput

0.493

High

1028997

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.489

High

1029018

CBP
CREB-binding protein

1

4

Small-scale

0.481

High

128976

MEN1
Menin

1

3

High-throughput

0.479

High

142941

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

241422

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

247832

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

272084

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

341553

EYA4
Protein phosphatase EYA4

1

7

High-throughput

0.479

High

345059

RIGI
Antiviral innate immune response receptor RIG-I

1

16

Small-scale

0.479

High

406077

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

443756

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

Small-scale

0.479

High

483899

HMOX1
Heme oxygenase 1

1

1

Small-scale

0.479

High

606639

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

695233

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

765400

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.479

High

766459

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

798999

BRCA1
Breast cancer type 1 susceptibility protein

1

10

High-throughput

0.479

High

830578

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

875630

PRC2A
Protein PRRC2A

1

9

High-throughput

0.479

High

1028967

OTUD4
OTU domain-containing protein 4

1

5

Small-scale

0.479

High

1028968

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1028971

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

1028984

PUM1
Pumilio homolog 1

1

8

High-throughput

0.479

High

1028985

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

1028986

CUL7
Cullin-7

1

5

High-throughput

0.479

High

1028992

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.479

High

1028994

SMN
Survival motor neuron protein

1

1

Small-scale

0.479

High

1028995

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

18

High-throughput

0.479

High

1029002

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1029003

SND1
Staphylococcal nuclease domain-containing protein 1

1

4

High-throughput

0.479

High

1029006

YTHD3
YTH domain-containing family protein 3

1

8

High-throughput

0.479

High

1029012

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1029017

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

1029026

FUBP3
Far upstream element-binding protein 3

1

20

High-throughput

0.479

High

1029027

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.479

High

1029030

PCGF1
Polycomb group RING finger protein 1

1

15

High-throughput

0.479

High

1029034

TRI31
E3 ubiquitin-protein ligase TRIM31

1

12

High-throughput

0.479

High

1029039

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1029040

NANOG
Homeobox protein NANOG

1

4

High-throughput

0.479

High

1029043

RNC
Ribonuclease 3

1

4

High-throughput

0.479

High

1029044

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

4

High-throughput

0.479

High

1029048

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

8

Small-scale

0.479

High

1029049

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1029053

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1017627

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.470

High

1028988

K1H1
Keratin, type I cuticular Ha1

1

0

High-throughput

0.460

High

518778

IL8
Interleukin-8

1

0

Small-scale

0.458

High

875922

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.458

High

1029014

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1029032

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

327950

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

18

High-throughput

0.445

High

952109

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

18

High-throughput

0.445

High

1028977

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.445

High

1029029

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.445

High

1029035

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

18

High-throughput

0.445

High

1029036

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

18

High-throughput

0.445

High

1029037

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

18

High-throughput

0.445

High

1017688

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

389301

FINC
Fibronectin

1

6

High-throughput

0.437

High

565351

ITA4
Integrin alpha-4

1

4

High-throughput

0.437

High

1029031

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.437

High

886760

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

1029011

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.407

High

1029045

USE1
Vesicle transport protein USE1

1

1

Small-scale

0.407

High

625860

AOC1
Diamine oxidase [copper-containing]

2

0

High-throughput

0.316

High

1028998

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1029042

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

1028993

AINX
Alpha-internexin

1

0

High-throughput

0.279

Low

1011252

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025