HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 667 Hs			1 449
+	Hs
		175670 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		175631 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		175671 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		933388 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		428490 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		934017 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		1175159 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		933810 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		933631 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		TBA4A_HUMAN (1-448): 0: 710: 89.96
+	Hs
		1171443 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		1175202 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		933491 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA4A_HUMAN (1-448): 0: 710: 89.96
+	Hs
		933246 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		1170530 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		1172004 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		428268 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		1161205 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA3E_HUMAN (1-439): 0: 693: 90.43
+	Hs
		933861 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		1282058 TRI63_HUMAN (1-380): 2.91e-86: 276: 24.09		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		1317527 TRI55_HUMAN (1-378): 3.73e-80: 266: 23.44		TBA8_HUMAN (1-449): 0: 700: 100.00