Protein: APBB2
Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1)

Gene: APBB2
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q92870

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001540 - amyloid-beta binding
GO:0001764 - neuron migration
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

395373

A4
Amyloid-beta precursor protein

9

14

Small-scale

0.972

High

987529

APLP2
Amyloid beta precursor like protein 2

4

15

Small-scale

0.895

High

120991

APBB1
Amyloid beta precursor protein binding family B member 1

3

3

High-throughput

0.861

High

849943

APLP1
Amyloid beta precursor like protein 1

3

13

High-throughput

0.861

High

1271901

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

3

0

High-throughput

0.816

High

232701

TBCD4
TBC1 domain family member 4

3

1

High-throughput

0.770

High

338796

EGFR
Epidermal growth factor receptor

4

5

High-throughput

0.699

High

980116

ATP7A
Copper-transporting ATPase 1

3

2

High-throughput

0.667

High

1271891

TGT
Queuine tRNA-ribosyltransferase catalytic subunit 1

3

1

High-throughput

0.667

High

1271906

FMN2
Formin-2

3

2

High-throughput

0.667

High

1271910

TBD2B
TBC1 domain family member 2B

3

2

High-throughput

0.667

High

1271870

APBB2
Amyloid beta precursor protein binding family B member 2

1

3

Small-scale

0.647

High

1271907

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.645

High

504508

HSP7C
Heat shock cognate 71 kDa protein

3

0

High-throughput

0.638

High

854117

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

3

0

High-throughput

0.638

High

1268843

AKAP1
A-kinase anchor protein 1, mitochondrial

3

0

High-throughput

0.638

High

1271886

APOL2
Apolipoprotein L2

3

0

High-throughput

0.638

High

1271893

LDH6B
L-lactate dehydrogenase A-like 6B

3

0

High-throughput

0.638

High

1271900

WDR41
WD repeat-containing protein 41

3

0

High-throughput

0.638

High

940517

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.618

High

1138020

SYDE2
Rho GTPase-activating protein SYDE2

3

3

High-throughput

0.609

High

1109754

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

914264

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.584

High

800816

MK08
Mitogen-activated protein kinase 8

1

2

Small-scale

0.561

High

548739

VAV
Proto-oncogene vav

1

1

High-throughput

0.536

High

59952

A4FUJ8
MKL1 protein

1

1

High-throughput

0.515

High

412289

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.515

High

568752

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.515

High

837832

MEOX1
Homeobox protein MOX-1

1

1

High-throughput

0.515

High

885451

VSX2
Visual system homeobox 2

1

1

High-throughput

0.515

High

1002057

ARL16
ADP-ribosylation factor-like protein 16

1

6

High-throughput

0.515

High

1128111

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.515

High

1157133

ESRP1
Epithelial splicing regulatory protein 1

1

2

High-throughput

0.515

High

1164966

SAS6
Spindle assembly abnormal protein 6 homolog

1

2

High-throughput

0.515

High

1191355

Q7Z637
protein-tyrosine-phosphatase

1

1

High-throughput

0.515

High

1235351

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.515

High

1271871

HDA10
Polyamine deacetylase HDAC10

1

1

High-throughput

0.515

High

1271872

OPTN
Optineurin

1

3

High-throughput

0.515

High

1271883

KCD15
BTB/POZ domain-containing protein KCTD15

1

1

High-throughput

0.515

High

1271889

SOX7
Transcription factor SOX-7

1

1

High-throughput

0.515

High

1271894

RAB6C
Ras-related protein Rab-6C

1

5

High-throughput

0.515

High

64062

AQ12B
Aquaporin-12B

1

0

High-throughput

0.513

High

577470

PACA
Pituitary adenylate cyclase-activating polypeptide

1

0

High-throughput

0.513

High

945210

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

0

High-throughput

0.513

High

387230

P53
Cellular tumor antigen p53

1

1

Small-scale

0.501

High

48065

E2F8
Transcription factor E2F8

1

0

High-throughput

0.493

High

66595

A8K878
cDNA FLJ77177, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors

1

0

High-throughput

0.493

High

177703

BIRC5
Baculoviral IAP repeat-containing protein 5

1

0

High-throughput

0.493

High

182370

PER1
Period circadian protein homolog 1

1

0

High-throughput

0.493

High

199205

ZNHI1
Zinc finger HIT domain-containing protein 1

1

0

High-throughput

0.493

High

204401

MS18B
Protein Mis18-beta

1

0

High-throughput

0.493

High

204510

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.493

High

234692

DLX3
Homeobox protein DLX-3

1

0

High-throughput

0.493

High

265237

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.493

High

277105

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.493

High

278142

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.493

High

318514

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.493

High

579221

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

0

High-throughput

0.493

High

595617

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.493

High

603218

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.493

High

624479

CCNC
Cyclin-C

1

0

High-throughput

0.493

High

800047

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

High-throughput

0.493

High

925965

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.493

High

941939

PITX1
Pituitary homeobox 1

1

0

High-throughput

0.493

High

974635

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.493

High

1024295

ZBT17
Zinc finger and BTB domain-containing protein 17

1

0

High-throughput

0.493

High

1033128

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

0

High-throughput

0.493

High

1039490

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

High-throughput

0.493

High

1085271

NRF1
Nuclear respiratory factor 1

1

0

High-throughput

0.493

High

1148592

NAIF1
Nuclear apoptosis-inducing factor 1

1

0

High-throughput

0.493

High

1150539

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.493

High

1159992

KLC3
Kinesin light chain 3

1

0

High-throughput

0.493

High

1161546

Q6PHZ7
NR2C2 protein

1

0

High-throughput

0.493

High

1161930

FOXR1
Forkhead box protein R1

1

0

High-throughput

0.493

High

1167220

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.493

High

1174916

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

0

High-throughput

0.493

High

1216890

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.493

High

1236353

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.493

High

1237396

SMIP4
Sperm-associated microtubule inner protein 4

1

0

High-throughput

0.493

High

1237540

ZN366
Zinc finger protein 366

1

0

High-throughput

0.493

High

1239918

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

0

High-throughput

0.493

High

1260716

PRUN2
Protein prune homolog 2

1

0

High-throughput

0.493

High

1270579

DPF1
Zinc finger protein neuro-d4

1

0

High-throughput

0.493

High

1271873

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.493

High

1271876

PP16A
Protein phosphatase 1 regulatory subunit 16A

1

0

High-throughput

0.493

High

1271877

ANCHR
Abscission/NoCut checkpoint regulator

1

0

High-throughput

0.493

High

1271878

BMF
Bcl-2-modifying factor

1

0

High-throughput

0.493

High

1271879

ZN488
Zinc finger protein 488

1

0

High-throughput

0.493

High

1271880

TIGD1
Tigger transposable element-derived protein 1

1

0

High-throughput

0.493

High

1271881

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.493

High

1271884

EYA3
Eyes absent homolog 3

1

0

High-throughput

0.493

High

1271887

ST4A1
Sulfotransferase 4A1

1

0

High-throughput

0.493

High

1271890

BBLN
Bublin coiled-coil protein

1

0

High-throughput

0.493

High

1271902

NXT2
NTF2-related export protein 2

1

0

High-throughput

0.493

High

1271909

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.493

High

1271911

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.493

High

1271912

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.493

High

1271913

MSRB2
Methionine-R-sulfoxide reductase B2, mitochondrial

1

0

High-throughput

0.493

High

981040

HGFA
Hepatocyte growth factor activator

1

2

High-throughput

0.489

High

1173136

SYDE1
Rho GTPase-activating protein SYDE1

1

3

High-throughput

0.489

High

1215953

WFDC8
WAP four-disulfide core domain protein 8

1

12

High-throughput

0.489

High

587657

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

Small-scale

0.480

High

155417

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

178709

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

212961

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

235985

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

2

High-throughput

0.479

High

507166

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

508133

FGFR1
Fibroblast growth factor receptor 1

1

5

High-throughput

0.479

High

526010

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

557760

NCK1
SH2/SH3 adapter protein NCK1

1

3

High-throughput

0.479

High

567207

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

591650

RAB3B
Ras-related protein Rab-3B

1

4

High-throughput

0.479

High

592418

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

601562

FGFR2
Fibroblast growth factor receptor 2

1

5

High-throughput

0.479

High

608074

FGFR4
Fibroblast growth factor receptor 4

1

5

High-throughput

0.479

High

845133

RAB7A
Ras-related protein Rab-7a

1

6

High-throughput

0.479

High

884558

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

890313

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

974961

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

990592

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

1017742

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1271885

SORT
Sortilin

1

1

High-throughput

0.479

High

1271888

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.479

High

1271899

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1271903

SAR1A
Small COPII coat GTPase SAR1A

1

4

High-throughput

0.479

High

1271908

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

130167

ELL2
RNA polymerase II elongation factor ELL2

1

1

High-throughput

0.470

High

1169885

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.470

High

1191401

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

4

High-throughput

0.470

High

1264334

MYLIP
E3 ubiquitin-protein ligase MYLIP

1

1

High-throughput

0.470

High

1075525

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

Small-scale

0.460

High

1175076

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.458

High

1188342

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1237434

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

1271897

GAN
Gigaxonin

1

0

High-throughput

0.458

High

1271905

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1271882

FRMD6
FERM domain-containing protein 6

1

1

High-throughput

0.445

High

791827

HD
Huntingtin

1

0

High-throughput

0.438

High

132556

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

845650

RAB9A
Ras-related protein Rab-9A

1

7

High-throughput

0.437

High

965779

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

1070335

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.437

High

1152018

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1230313

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

1271892

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.437

High

312834

CCN6
Cellular communication network factor 6

3

0

High-throughput

0.347

High

1271896

OSBL2
Oxysterol-binding protein-related protein 2

3

0

High-throughput

0.347

High

514447

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

785682

ASIP
Agouti-signaling protein

1

0

High-throughput

0.279

Low

81586

B7Z3E8
cDNA FLJ51208

1

0

High-throughput

0.268

Low

174423

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.268

Low

856279

HXK3
Hexokinase-3

1

0

High-throughput

0.268

Low

1023519

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.268

Low

1121687

Q53NU3
cDNA, FLJ92284

1

0

High-throughput

0.268

Low

1140517

VCF2
Protein VCF2

1

0

High-throughput

0.268

Low

1160796

AB17C
Alpha/beta hydrolase domain-containing protein 17C

1

0

High-throughput

0.268

Low

1167651

ASCL4
Achaete-scute homolog 4

1

0

High-throughput

0.268

Low

1169556

Q6ZP95
cDNA FLJ26194 fis, clone ADG06758

1

0

High-throughput

0.268

Low

1185444

Q7L8T7
cDNA FLJ40572 fis, clone THYMU2006170

1

0

High-throughput

0.268

Low

1191819

SPT12
Spermatogenesis-associated protein 12

1

0

High-throughput

0.268

Low

1215962

KR191
Keratin-associated protein 19-1

1

0

High-throughput

0.268

Low

1216038

KRA81
Keratin-associated protein 8-1

1

0

High-throughput

0.268

Low

1223223

SHLD1
Shieldin complex subunit 1

1

0

High-throughput

0.268

Low

1229608

CF218
Putative uncharacterized protein encoded by LINC00518

1

0

High-throughput

0.268

Low

1253282

ENKUR
Enkurin

1

0

High-throughput

0.268

Low

1254620

HUMMR
Protein MGARP

1

0

High-throughput

0.268

Low

1271874

ZHX1R
Zinc fingers and homeoboxes protein 1, isoform 2

1

0

High-throughput

0.268

Low

1271875

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.268

Low

1271895

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.268

Low

1271898

Q9H669
cDNA: FLJ22558 fis, clone HSI01557

1

0

High-throughput

0.268

Low

1271904

S6A13
Sodium- and chloride-dependent GABA transporter 2

1

0

High-throughput

0.268

Low

1271914

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.268

Low

1146693

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024