HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 664
+	Hs
		531540 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		K2C5_HUMAN (24-390): 2.24e-117: 364: 25.95
+	Hs
		359880 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		297444 TOX4_HUMAN (89-161): 7.09e-27: 108: 38.36		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		175746 HMGB3_HUMAN (13-180): 3.31e-46: 152: 100.00		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		359857 TFAM_HUMAN (93-191): 1.78e-10: 60.1: 21.21		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		817952 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68
+	Hs
		595134 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		449516 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43
+	Mm
		539724 SOX2_MOUSE (3-94): 3.52e-11: 62.8: 27.17		LMNB1_MOUSE (6-580): 8.76e-53: 193: 54.17
+	Hs
		297449 TOX4_HUMAN (89-161): 7.09e-27: 108: 38.36		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Mm
		589617 SOX2_MOUSE (3-94): 3.52e-11: 62.8: 27.17		VIME_MOUSE (27-394): 8.69e-32: 130: 29.35