HitPredict

Interactor 1: GPR37 (O15354)
Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR)
Gene: GPR37

Interactor 2: ADRB2 (P07550)
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Gene: ADRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 28298427, 24561123
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005886 - plasma membrane
GO:0043235 - receptor complex
GO:0043410 - positive regulation of MAPK cascade
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 613
Hs

1 413
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024