HitPredict

Interactor 1: PPM1G (O15355)
Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma)
Gene: PPM1G

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	24981860, 35271311, 28514442, 33961781, 18406329
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 546 Hs			1 143
+	Hs
		176229 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97
+	Hs
		176256 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19
+	Hs
		176095 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		176104 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		176209 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A2A_HUMAN (1-129): 7e-66: 197: 91.47
+	Hs
		176196 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70
+	Hs
		176267 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60
+	Hs
		175368 PPM1D_HUMAN (191-508): 3.13e-74: 248: 21.53		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		273452 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97
+	Hs
		273341 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		273353 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		260683 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69