Interactor 1: SHIP2 (O15357)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Gene: INPPL1

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.683

The method score is based on:

Property Details
Experiments 18692052
Identification Methods two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2, SH2~SH3_1, SH2~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0030027 - lamellipodium
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1258
Hs

1 1721
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024