HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: ZEB1 (P37275)
Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8)
Gene: ZEB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34462429
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1037 Hs			1 1124
+	Hs
		64130 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN729_HUMAN (555-1124): 1.05e-127: 422: 13.44
+	Hs
		67421 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN850_HUMAN (593-1123): 9.62e-129: 422: 12.95
+	Hs
		64132 IPO7_HUMAN (1-1031): 0: 819: 64.57		ZN729_HUMAN (555-1124): 1.05e-127: 422: 13.44
+	Hs
		178276 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN160_HUMAN (572-1124): 4.49e-113: 372: 12.98
+	Hs
		178224 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN565_HUMAN (53-377): 5.08e-96: 318: 16.48
+	Hs
		178275 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN287_HUMAN (409-874): 1.95e-83: 290: 5.75
+	Hs
		178234 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN480_HUMAN (750-1038): 6.45e-82: 279: 18.31
+	Hs
		178245 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN479_HUMAN (54-340): 3.68e-77: 265: 16.72
+	Hs
		178285 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN629_HUMAN (378-1075): 1.04e-59: 223: 8.44
+	Hs
		178182 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN484_HUMAN (789-1123): 1.72e-56: 213: 10.39
+	Hs
		178192 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZFP1_HUMAN (867-1041): 2.14e-58: 208: 26.26
+	Hs
		312288 IPO7_HUMAN (1-1031): 0: 819: 64.57		ZN484_HUMAN (789-1123): 1.72e-56: 213: 10.39
+	Hs
		178102 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZNF3_HUMAN (289-398): 2.34e-39: 154: 16.39
+	Hs
		178153 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN543_HUMAN (410-823): 6.18e-35: 144: 6.04
+	Hs
		178174 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZNF74_HUMAN (264-398): 4.02e-30: 129: 14.82
+	Hs
		178173 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZNF79_HUMAN (967-1122): 4.33e-25: 112: 13.46
+	Hs
		178165 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN846_HUMAN (923-1078): 1.78e-13: 76.4: 11.59
+	Hs
		178236 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN566_HUMAN (967-1092): 5.86e-13: 74.4: 15.87
+	Hs
		178194 IPO8_HUMAN (1-1037): 0: 846: 100.00		ZN773_HUMAN (221-286): 9.9e-10: 64.3: 48.49
+	Hs
		312270 IPO7_HUMAN (1-1031): 0: 819: 64.57		ZN846_HUMAN (923-1078): 1.78e-13: 76.4: 11.59