HitPredict

Interactor 1: STX7 (O15400)
Syntaxin-7
Gene: STX7

Interactor 2: YKT6 (O15498)
Synaptobrevin homolog YKT6 (EC 2.3.1.-)
Gene: YKT6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.922

Property	Details
Experiments	26186194, 28514442, 34079125, 33961781, 33422265
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005768 - endosome GO:0005886 - plasma membrane GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Hs			1 198
+	Dm
		1098114 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74
+	Hs
		178331 STX7_HUMAN (1-261): 9.25e-70: 217: 100.00		SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60
+	Mm
		936372 Q8BH40_MOUSE (1-259): 1.02e-74: 229: 94.98		VAMP7_MOUSE (28-193): 7.9e-57: 180: 22.60
+	Hs
		180894 STX12_HUMAN (10-244): 3.42e-58: 188: 54.01		YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00
+	Hs
		263179 STX2_HUMAN (7-256): 2.04e-65: 207: 27.13		SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60
+	Mm
		139056 STX1A_MOUSE (7-259): 3.19e-65: 206: 24.90		SC22B_MOUSE (1-196): 2.72e-63: 196: 19.60
+	Hs
		263248 STX1A_HUMAN (6-259): 6.04e-65: 205: 24.05		SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60
+	At
		955702 SYP22_ARATH (3-245): 3.86e-59: 190: 29.63		VA721_ARATH (22-194): 3.17e-68: 209: 21.51
+	Hs
		178445 STX7_HUMAN (1-261): 9.25e-70: 217: 100.00		VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03
+	Dm
		115805 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		M9PGI6_DROME (3-195): 3.74e-59: 185: 21.03
+	Rn
		699183 STX1A_RAT (7-259): 2.77e-65: 206: 24.90		VAMP7_RAT (28-193): 3.65e-57: 181: 23.16
+	Hs
		850569 STX1A_HUMAN (6-259): 6.04e-65: 205: 24.05		VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03
+	Hs
		263279 STX12_HUMAN (10-244): 3.42e-58: 188: 54.01		SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60
+	Dm
		1098086 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		Q7JYX5_DROME (28-194): 7.94e-54: 172: 25.84
+	At
		221561 SYP22_ARATH (3-245): 3.86e-59: 190: 29.63		VA711_ARATH (28-193): 1.87e-56: 179: 20.79
+	Hs
		850580 STX12_HUMAN (10-244): 3.42e-58: 188: 54.01		VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03
+	At
		955681 SYP22_ARATH (3-245): 3.86e-59: 190: 29.63		VA713_ARATH (27-192): 6.23e-56: 178: 21.23
+	At
		955679 SYP22_ARATH (3-245): 3.86e-59: 190: 29.63		VA714_ARATH (28-193): 3.77e-53: 170: 17.88
+	Hs
		699279 STX2_HUMAN (7-256): 2.04e-65: 207: 27.13		SC22A_HUMAN (1-147): 6.76e-29: 110: 16.23
+	Hs
		1083976 STX1A_HUMAN (6-259): 6.04e-65: 205: 24.05		SC22A_HUMAN (1-147): 6.76e-29: 110: 16.23