Protein: PKHH3
Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3)

Gene: PKHH3, PLEKHH3
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q7Z736

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

788953

TGFR2
TGF-beta receptor type-2

3

2

High-throughput

0.861

High

1280654

SKAP1
Src kinase-associated phosphoprotein 1

3

9

High-throughput

0.770

High

463999

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

8

High-throughput

0.618

High

845447

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

1

High-throughput

0.609

High

914439

EFNB2
Ephrin-B2

3

1

High-throughput

0.609

High

665045

IL4RA
Interleukin-4 receptor subunit alpha

2

1

High-throughput

0.574

High

724692

MK04
Mitogen-activated protein kinase 4

2

3

High-throughput

0.574

High

71389

HECA2
HEPACAM family member 2

2

4

High-throughput

0.558

High

158577

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

2

1

High-throughput

0.558

High

412178

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.553

High

1119650

KCNC3
Voltage-gated potassium channel KCNC3

1

5

High-throughput

0.536

High

1280670

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

1

1

High-throughput

0.536

High

1007872

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1280669

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

1280672

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.513

High

158462

RFXK
DNA-binding protein RFXANK

1

1

High-throughput

0.489

High

190412

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.489

High

848513

MAGA8
Melanoma-associated antigen 8

1

6

High-throughput

0.489

High

868327

V1BR
Vasopressin V1b receptor

1

1

High-throughput

0.489

High

956921

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.489

High

1022896

EFNB1
Ephrin-B1

1

1

High-throughput

0.489

High

1116819

AVR2B
Activin receptor type-2B

1

2

High-throughput

0.489

High

1144047

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.489

High

1161847

AMHR2
Anti-Muellerian hormone type-2 receptor

1

2

High-throughput

0.489

High

1177014

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1249803

BTNL9
Butyrophilin-like protein 9

1

2

High-throughput

0.489

High

1280659

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

3

High-throughput

0.489

High

1280666

SLIK6
SLIT and NTRK-like protein 6

1

2

High-throughput

0.489

High

1280674

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

1280675

PTC2
Protein patched homolog 2

1

1

High-throughput

0.489

High

1280676

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.489

High

106190

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

178309

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High

293934

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

830992

CCNF
Cyclin-F

1

3

High-throughput

0.437

High

872479

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

888162

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

1045455

TF65
Transcription factor p65

1

3

High-throughput

0.437

High

219443

S26A4
Pendrin

1

1

High-throughput

0.407

High

1133785

SL9A5
Sodium/hydrogen exchanger 5

1

1

High-throughput

0.407

High

1280658

HAVR2
Hepatitis A virus cellular receptor 2

2

0

High-throughput

0.328

High

1280667

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.328

High

938115

ANM2
Protein arginine N-methyltransferase 2

2

0

High-throughput

0.298

High

475987

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

0

High-throughput

0.279

Low

711562

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

952502

CTXN1
Cortexin-1

1

0

High-throughput

0.279

Low

1280653

T200A
Transmembrane protein 200A

1

0

High-throughput

0.279

Low

1280655

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1280657

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.279

Low

1280660

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

1280661

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.279

Low

1280662

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

0

High-throughput

0.279

Low

1280663

OPALI
Opalin

1

0

High-throughput

0.279

Low

1280664

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1280668

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1280671

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.279

Low

1280673

TMED7
Transmembrane emp24 domain-containing protein 7

1

0

High-throughput

0.279

Low

952222

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.261

Low

1238994

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.232

Low

1280656

SPX3
Sugar phosphate exchanger 3

1

0

High-throughput

0.232

Low

1280665

S13A1
Solute carrier family 13 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025