Interactor 1: ARPC2 (O15144)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARPC2

Interactor 2: ARPC3 (O15145)
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Gene: ARPC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 23148219, 24981860, 38367669, 28524877, 11805826
Identification Methods affinity chromatography technology, pull down, biochemical, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
and 7 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 300
Hs

1 178
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025