Protein: ARPC3
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)

Gene: ARPC3, ARC18
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: Q05933

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005739 - mitochondrion
GO:0005885 - Arp2/3 protein complex
GO:0015629 - actin cytoskeleton
GO:0030833 - regulation of actin filament polymerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736137

ARP2
Actin-related protein 2

13

7

Small-scale

0.981

High

865588

ARP3
Actin-related protein 3

7

8

Small-scale

0.963

High

798166

ARPC1
Actin-related protein 2/3 complex subunit 1

7

5

Small-scale

0.750

High

750345

ARPC4
Actin-related protein 2/3 complex subunit 4

7

5

Small-scale

0.748

High

922984

ARPC2
Actin-related protein 2/3 complex subunit 2

6

2

Small-scale

0.728

High

825851

ARPC5
Actin-related protein 2/3 complex subunit 5

5

3

Small-scale

0.714

High

1052976

LAS17
Proline-rich protein LAS17

4

4

Small-scale

0.690

High

1052969

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.663

High

1046640

MYO5
Myosin-5

3

4

Small-scale

0.658

High

598919

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

2

0

High-throughput

0.576

High

751879

SLA2
Protein SLA2

2

2

High-throughput

0.561

High

790591

VRP1
Verprolin

2

0

High-throughput

0.551

High

605346

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.518

High

623950

MYO2
Myosin-2

1

3

Small-scale

0.481

High

836337

BNI1
Protein BNI1

1

0

High-throughput

0.480

High

1052974

AIM7
Protein AIM7

1

0

Small-scale

0.480

High

744925

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.479

High

779022

MYO3
Myosin-3

1

6

High-throughput

0.479

High

809232

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.479

High

1052972

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

1

Small-scale

0.479

High

580083

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

739095

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

0

High-throughput

0.458

High

1052971

PIN3
[PSI+] inducibility protein 3

1

1

Small-scale

0.439

High

803690

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

829767

GTS1
Protein GTS1

1

1

High-throughput

0.437

High

1052322

ENT2
Epsin-2

1

1

High-throughput

0.437

High

1052977

ENT1
Epsin-1

1

1

High-throughput

0.437

High

644842

CLH
Clathrin heavy chain

2

0

High-throughput

0.320

High

438491

EIF3B
Eukaryotic translation initiation factor 3 subunit B

2

0

High-throughput

0.313

High

836101

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.282

High

817441

VHR2
Transcription factor VHR2

1

0

High-throughput

0.269

Low

649674

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.261

Low

1052970

CORO
Coronin-like protein

1

0

Small-scale

0.261

Low

708210

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

740433

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.249

Low

812665

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1046172

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

1052973

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

Small-scale

0.249

Low

1052975

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

1052978

HUG1
MEC1-mediated checkpoint protein HUG1

1

0

High-throughput

0.238

Low

819821

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025