Interactor 1: ARPC2 (O15144)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARPC2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 20876399, unassigned1853
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003779 - actin binding
GO:0005654 - nucleoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0030672 - synaptic vesicle membrane
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 300
Hs

1 2527
+ Mm

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Last updated: 11Aug2025