Interactor 1: TLR3 (O15455)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Interactor 2: UN93B (Q9H1C4)
Protein unc-93 homolog B1 (Unc-93B1) (hUNC93B1)
Gene: UNC93B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 31604943, 22164301
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0002224 - toll-like receptor signaling pathway
GO:0005789 - endoplasmic reticulum membrane
GO:0032735 - positive regulation of interleukin-12 production
GO:0032755 - positive regulation of interleukin-6 production
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 904
Hs

1 597
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024