Interactor 1: PACN1 (Q9BY11)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: PACSIN1

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 25416956, 11082044, 28514442, 32296183, 33961781, unassigned1304, 31515488
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FCH~FCH, FCH~SH3_9, SH3_9~SH3_9
Common GO terms GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 444
Hs

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Last updated: 15 Jul 2024