Interactor 1: MSH4 (O15457)
MutS protein homolog 4 (hMSH4)
Gene: MSH4

Interactor 2: MSH5 (O43196)
MutS protein homolog 5 (hMSH5)
Gene: MSH5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 12591739, 9787078, 10029069, 16397227, 15489243, 32814343, 16122992, 22401567
Identification Methods two hybrid, pull down, affinity chromatography technology, biochemical, protein three hybrid, coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V
Common GO terms GO:0003690 - double-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
GO:0030983 - mismatched DNA binding
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 936
Hs

1 834
+ Hs
+ Hs
+ Mm
+ Hs
+ Dr
+ At
+ At
+ At
+ Sc
+ Sc
+ Ec
+ Ce
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024