Protein: TR10A
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)

Gene: TR10A, TNFRSF10A
Organism: Homo sapiens
Interactions: 132
UniProt ID: O00220

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0005035 - death receptor activity
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

121480

FADD
FAS-associated death domain protein

13

20

Small-scale

0.977

High

121420

TR10B
Tumor necrosis factor receptor superfamily member 10B

5

16

Small-scale

0.927

High

121456

TNF10
Tumor necrosis factor ligand superfamily member 10

5

20

Small-scale

0.908

High

121484

CASP8
Caspase-8

17

16

Small-scale

0.763

High

121422

CFLAR
CASP8 and FADD-like apoptosis regulator

5

16

Small-scale

0.699

High

121441

FGFR4
Fibroblast growth factor receptor 4

1

19

High-throughput

0.691

High

121442

FGFR3
Fibroblast growth factor receptor 3

1

19

High-throughput

0.691

High

121444

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

2

High-throughput

0.691

High

121448

CD70
CD70 antigen

1

1

High-throughput

0.691

High

121451

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

4

High-throughput

0.691

High

121500

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.691

High

121516

BT2A2
Butyrophilin subfamily 2 member A2

1

1

High-throughput

0.691

High

121428

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.656

High

121417

SDCB1
Syntenin-1

2

3

High-throughput

0.628

High

121432

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

7

High-throughput

0.628

High

121449

BMR1A
Bone morphogenetic protein receptor type-1A

2

7

High-throughput

0.628

High

121463

MFAP3
Microfibril-associated glycoprotein 3

2

1

High-throughput

0.628

High

121504

LRP10
Low-density lipoprotein receptor-related protein 10

2

1

High-throughput

0.628

High

121506

FBX11
F-box only protein 11

2

1

High-throughput

0.628

High

121536

CD320
CD320 antigen

2

1

High-throughput

0.628

High

121541

S12A4
Solute carrier family 12 member 4

2

3

High-throughput

0.628

High

121427

BCL10
B-cell lymphoma/leukemia 10

1

2

Small-scale

0.621

High

121485

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

9

Small-scale

0.618

High

121509

CARME
Carnosine N-methyltransferase

2

0

High-throughput

0.602

High

121488

CEGT
Ceramide glucosyltransferase

2

1

High-throughput

0.574

High

121502

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

1

High-throughput

0.574

High

121482

CUL3
Cullin-3

2

5

Small-scale

0.571

High

121517

CASPA
Caspase-10

2

16

Small-scale

0.571

High

61891

MP3B2
Microtubule-associated proteins 1A/1B light chain 3 beta 2

1

1

High-throughput

0.536

High

68512

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

1

High-throughput

0.536

High

121419

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.536

High

121423

ADCY6
Adenylate cyclase type 6

1

1

High-throughput

0.536

High

121426

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

High-throughput

0.536

High

121439

INAR1
Interferon alpha/beta receptor 1

1

5

High-throughput

0.536

High

121445

IL4RA
Interleukin-4 receptor subunit alpha

1

3

High-throughput

0.536

High

121446

AVR2A
Activin receptor type-2A

1

7

High-throughput

0.536

High

121450

TGFR2
TGF-beta receptor type-2

1

7

High-throughput

0.536

High

121453

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

4

High-throughput

0.536

High

121455

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.536

High

121457

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.536

High

121465

S10AA
Protein S100-A10

1

3

High-throughput

0.536

High

121471

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.536

High

121473

AT11A
Phospholipid-transporting ATPase IH

1

3

High-throughput

0.536

High

121474

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.536

High

121475

ACVR1
Activin receptor type-1

1

7

High-throughput

0.536

High

121476

LG3BP
Galectin-3-binding protein

1

2

High-throughput

0.536

High

121481

SQSTM
Sequestosome-1

1

4

Small-scale

0.536

High

121495

STEA3
Metalloreductase STEAP3

1

1

High-throughput

0.536

High

121497

TM214
Transmembrane protein 214

1

3

High-throughput

0.536

High

121498

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.536

High

121505

LAP4B
Lysosomal-associated transmembrane protein 4B

1

2

High-throughput

0.536

High

121507

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.536

High

121510

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.536

High

121512

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

1

High-throughput

0.536

High

121520

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

3

High-throughput

0.536

High

121527

CDC6
Cell division control protein 6 homolog

1

7

High-throughput

0.536

High

121528

MEP50
Methylosome protein WDR77

1

2

High-throughput

0.536

High

121529

NFIP1
NEDD4 family-interacting protein 1

1

1

High-throughput

0.536

High

121537

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

121538

GPC5B
G-protein coupled receptor family C group 5 member B

1

4

High-throughput

0.536

High

121543

S4A7
Sodium bicarbonate cotransporter 3

1

1

High-throughput

0.536

High

121494

MARH8
E3 ubiquitin-protein ligase MARCHF8

2

6

Small-scale

0.533

High

121421

GLYG2
Glycogenin-2

1

0

High-throughput

0.513

High

121430

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.513

High

121435

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.513

High

121437

CD44
CD44 antigen

1

0

High-throughput

0.513

High

121459

GALK1
Galactokinase

1

0

High-throughput

0.513

High

121468

1433G
14-3-3 protein gamma

1

0

High-throughput

0.513

High

121490

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

121499

KCNT2
Potassium channel subfamily T member 2

1

0

High-throughput

0.513

High

121503

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

121518

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

High-throughput

0.513

High

121530

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.513

High

121539

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

121542

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

121524

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

3

Small-scale

0.506

High

121458

RT29
Small ribosomal subunit protein mS29

1

1

Small-scale

0.504

High

121425

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

1

High-throughput

0.489

High

121429

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

121462

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

5

High-throughput

0.489

High

121477

TMM94
Transmembrane protein 94

1

1

High-throughput

0.489

High

121478

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.489

High

121489

LSM12
Protein LSM12

1

1

High-throughput

0.489

High

121492

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

121508

LRC47
Leucine-rich repeat-containing protein 47

1

2

High-throughput

0.489

High

121511

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.489

High

121519

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.489

High

121521

P5CR2
Pyrroline-5-carboxylate reductase 2

1

1

High-throughput

0.489

High

121523

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.489

High

121540

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

2

High-throughput

0.489

High

120192

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

121431

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

121434

UBL4A
Ubiquitin-like protein 4A

1

10

High-throughput

0.479

High

121436

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

121438

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

121440

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

7

Small-scale

0.479

High

121443

CBL
E3 ubiquitin-protein ligase CBL

1

10

Small-scale

0.479

High

121461

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

121464

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

121466

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

121467

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

121469

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

121470

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

121472

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

121479

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.479

High

121486

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

121501

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

121513

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

6

Small-scale

0.479

High

121534

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

121535

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

121525

PARK7
Parkinson disease protein 7

1

0

Small-scale

0.458

High

121491

Q5HY81
Ubiquitin-like protein 4A

1

10

High-throughput

0.445

High

121496

OTU7B
OTU domain-containing protein 7B

1

7

Small-scale

0.445

High

121526

NP1L4
Nucleosome assembly protein 1-like 4

1

3

High-throughput

0.437

High

68502

A8MXH2
Nucleosome assembly protein 1-like 4

1

3

High-throughput

0.407

High

121447

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

1

High-throughput

0.407

High

121454

LSS
Lanosterol synthase

2

0

High-throughput

0.328

High

121493

PR15B
Protein phosphatase 1 regulatory subunit 15B

2

0

High-throughput

0.288

High

87447

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

0

High-throughput

0.279

Low

121418

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.279

Low

121424

IDH3B
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

1

0

High-throughput

0.279

Low

121452

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.279

Low

121460

CLCN7
H(+)/Cl(-) exchange transporter 7

1

0

High-throughput

0.279

Low

121483

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

121487

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.279

Low

121514

ST7L
Suppressor of tumorigenicity 7 protein-like

1

0

High-throughput

0.279

Low

121515

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

121522

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.279

Low

121531

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

121532

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.279

Low

121533

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.279

Low

121433

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024