Interactor 1: MSH4 (O15457)
MutS protein homolog 4 (hMSH4)
Gene: MSH4

Interactor 2: MLH3 (Q9UHC1)
DNA mismatch repair protein Mlh3 (MutL protein homolog 3)
Gene: MLH3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 32814904, 12095912
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~MutS_II, HATPase_c_3~MutS_III, HATPase_c_3~MutS_V
Common GO terms GO:0000795 - synaptonemal complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
GO:0007131 - reciprocal meiotic recombination
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 936
Hs

1 1453
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
+ Ec
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024