HitPredict

Interactor 1: CCL16 (O15467)
C-C motif chemokine 16 (Chemokine CC-4) (HCC-4) (Chemokine LEC) (IL-10-inducible chemokine) (LCC-1) (Liver-expressed chemokine) (Lymphocyte and monocyte chemoattractant) (LMC) (Monotactin-1) (MTN-1) (NCC-4) (Small-inducible cytokine A16)
Gene: CCL16

Interactor 2: CCR8 (P51685)
C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198)
Gene: CCR8

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10910894
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 120 Hs			1 355
+	Hs
		849619 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64
+	Hs
		561732 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64
+	Hs
		526564 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR3_HUMAN (1-346): 6.44e-92: 280: 37.64
+	Hs
		180159 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CXCR5_HUMAN (3-346): 3.32e-81: 253: 27.71
+	Hs
		134400 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33
+	Hs
		1305163 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		ACKR4_HUMAN (5-317): 7.32e-82: 254: 31.17
+	Hs
		180160 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR2_HUMAN (6-328): 2.8e-77: 243: 39.51
+	Hs
		180158 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR1_HUMAN (15-345): 6.58e-77: 242: 41.44
+	Hs
		134356 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33
+	Hs
		134354 CCL3_HUMAN (1-95): 8.52e-33: 112: 32.29		ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33
+	Hs
		526561 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CXCR5_HUMAN (3-346): 3.32e-81: 253: 27.71
+	Mm
		500591 CCL3_MOUSE (1-95): 9.34e-34: 114: 37.50		CCR3_MOUSE (9-345): 4.69e-79: 247: 41.30
+	Hs
		783833 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR2_HUMAN (6-328): 2.8e-77: 243: 39.51
+	Hs
		180161 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR5_HUMAN (1-352): 1.66e-72: 230: 40.11
+	Hs
		561728 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR1_HUMAN (15-345): 6.58e-77: 242: 41.44
+	Hs
		526560 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR1_HUMAN (15-345): 6.58e-77: 242: 41.44
+	Hs
		849654 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR5_HUMAN (1-352): 1.66e-72: 230: 40.11
+	Hs
		561733 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR5_HUMAN (1-352): 1.66e-72: 230: 40.11
+	Hs
		526565 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR5_HUMAN (1-352): 1.66e-72: 230: 40.11
+	Mm
		500590 CCL3_MOUSE (1-95): 9.34e-34: 114: 37.50		CCR1_MOUSE (3-345): 6.18e-72: 229: 39.13