Protein: ZBT49
Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)

Gene: ZBT49, ZBTB49
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q6ZSB9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001223 - transcription coactivator binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1254099

ZBT8A
Zinc finger and BTB domain-containing protein 8A

3

20

High-throughput

0.871

High

1254096

ZBTB2
Zinc finger and BTB domain-containing protein 2

2

16

High-throughput

0.783

High

1094501

ZBT17
Zinc finger and BTB domain-containing protein 17

1

17

Small-scale

0.724

High

1254104

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

5

2

High-throughput

0.722

High

1254097

CEP70
Centrosomal protein of 70 kDa

3

1

High-throughput

0.676

High

1090735

TRAF2
TNF receptor-associated factor 2

3

20

High-throughput

0.654

High

1254101

HINFP
Histone H4 transcription factor

1

13

Small-scale

0.618

High

1065957

VAC14
Protein VAC14 homolog

2

2

High-throughput

0.606

High

1094916

TRAF3
TNF receptor-associated factor 3

2

20

High-throughput

0.606

High

1254100

CIB1
Calcium and integrin-binding protein 1

2

3

High-throughput

0.606

High

1254105

PICK1
PRKCA-binding protein

2

3

High-throughput

0.606

High

414072

P53
Cellular tumor antigen p53

1

9

Small-scale

0.561

High

1067449

EP300
Histone acetyltransferase p300

1

9

Small-scale

0.561

High

1254107

FXL17
F-box/LRR-repeat protein 17

1

0

High-throughput

0.546

High

1032345

OTUD4
OTU domain-containing protein 4

1

1

High-throughput

0.536

High

822727

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.515

High

1228300

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.513

High

593762

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.493

High

1254103

WDR83
WD repeat domain-containing protein 83

1

1

High-throughput

0.489

High

242069

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

461622

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

468521

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

623399

RO52
E3 ubiquitin-protein ligase TRIM21

1

16

High-throughput

0.479

High

1155480

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

Small-scale

0.479

High

1254098

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

1254106

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.460

High

1147188

ELOB
Elongin-B

1

0

High-throughput

0.458

High

1254102

PSD2
PH and SEC7 domain-containing protein 2

1

0

High-throughput

0.279

Low

565643

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.268

Low

1254094

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.249

Low

1254095

CFA46
Cilia- and flagella-associated protein 46

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025