HitPredict

Interactor 1: GSC2 (O15499)
Homeobox protein goosecoid-2 (GSC-2) (Homeobox protein goosecoid-like) (GSC-L)
Gene: GSC2

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 735
+	Hs
		1151294 Q6FHY5_HUMAN (37-191): 6.64e-33: 121: 27.39		TRIM1_HUMAN (1-735): 0: 592: 100.00
+	Hs
		838347 MEOX2_HUMAN (37-191): 6.78e-33: 121: 27.39		TRIM1_HUMAN (1-735): 0: 592: 100.00
+	Hs
		567902 HXB9_HUMAN (1-191): 2.36e-32: 118: 19.69		TRIM1_HUMAN (1-735): 0: 592: 100.00
+	Hs
		175642 PAX6_HUMAN (123-194): 9.8e-34: 125: 48.61		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		1052746 PITX2_HUMAN (116-186): 1e-16: 78.6: 57.75		TRI25_HUMAN (24-706): 9.41e-99: 319: 20.96
+	Hs
		1033368 Q6FHY5_HUMAN (37-191): 6.64e-33: 121: 27.39		BT1A1_HUMAN (501-729): 3.88e-80: 267: 21.19
+	Hs
		837958 MEOX2_HUMAN (37-191): 6.78e-33: 121: 27.39		BT1A1_HUMAN (501-729): 3.88e-80: 267: 21.19
+	Hs
		686493 OTX1_HUMAN (79-200): 1.17e-35: 129: 39.34		TRI42_HUMAN (24-422): 6.87e-73: 252: 22.87
+	Hs
		1151106 Q6FHY5_HUMAN (37-191): 6.64e-33: 121: 27.39		TRI42_HUMAN (24-422): 6.87e-73: 252: 22.87
+	Hs
		838104 MEOX2_HUMAN (37-191): 6.78e-33: 121: 27.39		TRI42_HUMAN (24-422): 6.87e-73: 252: 22.87
+	Hs
		1151244 Q6FHY5_HUMAN (37-191): 6.64e-33: 121: 27.39		TRI45_HUMAN (29-379): 2.85e-68: 237: 20.59
+	Hs
		838283 MEOX2_HUMAN (37-191): 6.78e-33: 121: 27.39		TRI45_HUMAN (29-379): 2.85e-68: 237: 20.59
+	Hs
		536730 PAX7_HUMAN (123-199): 4.66e-34: 128: 51.25		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		641517 PAX6_HUMAN (123-194): 9.8e-34: 125: 48.61		TRI11_HUMAN (16-269): 1.65e-24: 109: 16.54
+	Mm
		926113 PAX6_MOUSE (123-194): 9.8e-34: 125: 48.61		TRI11_MOUSE (16-269): 2.33e-23: 105: 16.14
+	Hs
		536721 HXB9_HUMAN (1-191): 2.36e-32: 118: 19.69		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		595623 HXA5_HUMAN (31-201): 5.85e-31: 115: 16.85		TRI11_HUMAN (16-269): 1.65e-24: 109: 16.54
+	Mm
		193313 PHX2B_MOUSE (41-186): 1.38e-30: 115: 29.05		TRI11_MOUSE (16-269): 2.33e-23: 105: 16.14
+	Hs
		734592 PITX1_HUMAN (120-186): 1.21e-14: 72.8: 55.22		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71