Interactor 1: INSI1 (O15503)
Insulin-induced gene 1 protein (INSIG-1)
Gene: INSIG1
Interactor 2: SRBP2 (Q12772)
Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)]
Gene: SREBF2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 0.60 | 0.584 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0032933 - SREBP signaling pathway GO:0032937 - SREBP-SCAP-Insig complex GO:0042632 - cholesterol homeostasis |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
